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Table 3 Clinical profiles of the patients whose plasma samples were analyzed by ELISA

From: Differential proteomic analysis of virus-enriched fractions obtained from plasma pools of patients with dengue fever or severe dengue

 

Colombian Patients

Cambodian Patients

 

DF (n = 15)

DS (n = 15)

P-value

DF (n = 23)

DS (n = 26)

P-value

Age, average ± SD (years)

29.3 ± 0.52

28.3 ± 0.5

ns

8.6 ± 0.38

7.3 ± 0.45

ns

% male

60 %

53 %

ns

56 %

35.6 %

ns

Sampling (day after onset)

3.06

2.37

ns

2.6

3.2

ns

Weight, average ± SD (Kg)

60.2 ± 8.6

50.3 ± 15.6

ns

20.48 ± 0.93

18.86 ± 0.98

ns

Total cholesterol (g/L)

1.44 ± 5.4

1.29 ± 10.1

0.03

1.28 ± 0.05

0.92 ± 0.046

<0.0001

Aspartate aminotransferase (IU/L)

90.2 ± 9.75

142.7 ± 29.8

0.001

133.3 ± 23.18

302.5 ± 50.7

0.0043

Alanine aminotransferase (IU/L)

69.7 ± 11.4

90.8 ± 24.5

ns

66.9 ± 13.4

106.3 ± 21.2

ns

Viral load (copy/mL)

4.05 × 106 ± 3.5

4.1 × 107 ± 5.22

0.006

7.1 108 ± 6

2.06 108 ± 2

ns

Positive Tourniquet test

8/15 (60 %)

10/15 (66 %)

ns

19/23 (82 %)

18/26 (82.6 %)

ns

Hepatomegaly on ultrasound

na

na

-

8/12 (66 %)

16/26 (61.5 %)

ns

Serotype

1-2-3

1-2-3

-

1

1

-

Secondary dengue infection

15 (100 %)

15 (100 %)

-

23 (100 %)

26 (100 %)

-

Comorbidity

0 (0 %)

0 (0 %)

-

0 (0 %)

0 (0 %)

-

  1. IU international units, ns not significant, na not applicable
  2. Chi-square or Mann–Whitney tests were used to analyze the differences between groups