Table 1 Baseline characteristics

Age, median (IQR)

47(37,53)

52(47,57)

<0.001

Race

0.99

White

69.21 %

69.31 %

Black

20.00 %

19.90 %

Hispanic

3.15 %

3.14 %

Other/not known

7.64 %

7.65 %

Gender (% male)

91.34 %

91.40 %

0.94

Body mass index, mean (kg/m²)

26.94(6.73)

28.15(5.98)

<0.001

Underweight (BMI <18.5)

1.02 %

2.37 %

0.003

Normal weight (BMI 18.5–24.9)

37.48 %

29.29 %

<0.001

Overweight (BMI 25–29.9)

39.69 %

36.21 %

0.02

Obese (BMI > =30)

21.81 %

32.13 %

<0.001

Diabetes

4.41 %

4.73 %

0.62

Hypertension

31.65 %

38.78 %

<0.001

Chronic kidney disease

13.78 %

15.50 %

0.13

Cardiovascular disease

3.39 %

4.18 %

0.2

Alcohol abuse or dependence

45.75 %

30.69 %

<0.001

Drug abuse or dependence

49.37 %

21.18 %

<0.001

ALT, mean (SD)

79.31(114.08)

33.28(22.48)

<0.001

AST, mean (SD)

56.36(67.91)

30.18(20.87)

<0.001

FIB-4, mean (SD)

1.39(1.7)

1.28(1.05)

0.03

Cirrhosis by FIB-4 > 3.5 (%)

4.86 %

2.95 %

<0.001

Total cholesterol, median (IQR)

178.5(154.5,199.5)

180(159,200)

0.02

> = 240 (%)

3.31 %

3.41 %

0.85

LDL, median (IQR)

103.5(83.7,122.5)

106(87.6,124.5)

0.003

> = 190 (%)

0.24 %

0.32 %

0.5

TG, median (IQR)

120(84,173)

110.75(77.5,159)

<0.001

> = 500 (%)

0.31 %

0.45 %

0.5

HDL, median (IQR)

45.5(37.4,55)

45.5(38,56.5)

0.04

<40 (%)

32.20 %

30.18 %

0.16

HCV RNA log 10 IU/ml, mean (SD)

4.28(2.81)

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HCV genotype

N/A

1

37.40 %

2

5.04 %

3

6.69 %

4

0.31 %

Not available

50.55 %