Skip to main content

Table 1 Baseline characteristics

From: Changes in circulating lipids level over time after acquiring HCV infection: results from ERCHIVES

Variable HCV+ Control* P-value
N = 1270 N = 5070  
Age, median (IQR) 47(37,53) 52(47,57) <0.001
Race    0.99
White 69.21 % 69.31 %  
Black 20.00 % 19.90 %  
Hispanic 3.15 % 3.14 %  
Other/not known 7.64 % 7.65 %  
Gender (% male) 91.34 % 91.40 % 0.94
Body mass index, mean (kg/m2) 26.94(6.73) 28.15(5.98) <0.001
Underweight (BMI <18.5) 1.02 % 2.37 % 0.003
Normal weight (BMI 18.5–24.9) 37.48 % 29.29 % <0.001
Overweight (BMI 25–29.9) 39.69 % 36.21 % 0.02
Obese (BMI > =30) 21.81 % 32.13 % <0.001
Diabetes 4.41 % 4.73 % 0.62
Hypertension 31.65 % 38.78 % <0.001
Chronic kidney disease 13.78 % 15.50 % 0.13
Cardiovascular disease 3.39 % 4.18 % 0.2
Alcohol abuse or dependence 45.75 % 30.69 % <0.001
Drug abuse or dependence 49.37 % 21.18 % <0.001
ALT, mean (SD) 79.31(114.08) 33.28(22.48) <0.001
AST, mean (SD) 56.36(67.91) 30.18(20.87) <0.001
FIB-4, mean (SD) 1.39(1.7) 1.28(1.05) 0.03
Cirrhosis by FIB-4 > 3.5 (%) 4.86 % 2.95 % <0.001
Total cholesterol, median (IQR) 178.5(154.5,199.5) 180(159,200) 0.02
> = 240 (%) 3.31 % 3.41 % 0.85
LDL, median (IQR) 103.5(83.7,122.5) 106(87.6,124.5) 0.003
> = 190 (%) 0.24 % 0.32 % 0.5
TG, median (IQR) 120(84,173) 110.75(77.5,159) <0.001
> = 500 (%) 0.31 % 0.45 % 0.5
HDL, median (IQR) 45.5(37.4,55) 45.5(38,56.5) 0.04
<40 (%) 32.20 % 30.18 % 0.16
HCV RNA log 10 IU/ml, mean (SD) 4.28(2.81) -- --
HCV genotype   N/A  
1 37.40 %   
2 5.04 %   
3 6.69 %   
4 0.31 %   
Not available 50.55 %   
  1. *Matched samples
  2. TC total cholesterol, LDL low density lipoproteins, HDL high density lipoprotein, TG triglycerides, non-HDL-C non-HDL cholesterol