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Table 2 Factors associated with Non-adherence to ART in bivariate and multivariate analysis

From: Adherence to antiretroviral therapy and retention in care for adolescents living with HIV from 10 districts in Uganda

Variable   Non adherence
N = 168 (9.6 %)
Adherence
N = 1588 (90.4 %)
Totals N = 1756 Crude OR (95 % CI) P value Adjusted OR (95 % CI) P value
Sex Female 93 (8.5) 1003 (91.5) 1096     
Male 75 (11.4) 585 (88.6) 660 1.38 [1.00 1.90] 0.048 1.33 [0.84 2.13] 0.224
Facility location Urban 132 (8.4) 1441 (91.6) 1573     
Rural 36 (19.7) 147 (80.3) 183 2.67 [1.78 4.01] 0.000 2.64 [1.28 5.43] 0.008
Age at initiation <15 years 122 (9.1) 1224 (90.9) 1346     
≥15 years 46 (11.2) 364 (88.8) 410 1.27 [0.88 1.81] 0.195   
Age at last encounter <15 years 89 (10.4) 765 (89.6) 854     
≥15 years 79 (8.8) 823 (91.2) 902 0.82 [0.60 1.13] 0.237   
Ownership of Health Facility Government 88 (7.9) 1022 (92.1) 1110     
Private 80 (12.4) 566 (87.6) 646 1.64 [1.19 2.25] 0.002 0.55 [0.06 4.77] 0.585
Level of HF Hospital 52 (5.6) 874 (94.4) 926     
Health Center 37 (18.6) 162 (81.4) 199 3.83 [2.43 6.04] 0.000 2.02 [0.97 4.22] 0.061
Duration on ART >1 year 85 (8.2) 949 (91.8) 1034     
≤1 year 83 (11.5) 639 (88.5) 725 1.45 [1.05 1.99] 0.022 1.56 [0.81 3.02] 0.183
>3 years 42 (7.0) 559 (93.0) 601     
≤3 years 126 (10.9) 1029 (89.1) 1155 1.63 [1.13 2.34] 0.009 0.63 [0.31 1.27] 0.195
Regimen at initiation EFV based 82 (10.3) 718 (89.7) 800     
NVP based 82 (9.1) 821 (90.9) 903 0.87 [0.63 1.20] 0.415   
LPV/r based 4 (11.1) 32 (88.9) 36 1.09 [0.37 3.17] 0.868   
  1. HF health facility, EFV Efavirenz, LPV/r Lopinavir/ritotanir, NVP Nevirapine
  2. The value in bold is the only one which is statistically significant and was intentionally put in bold in order for it to stand out