|
Outcome
|
Unadjusted (PAS)
|
Adjusted (MVAS)
|
|---|
|
Daptomycin (n = 118)
|
Vancomycin (n = 106)
|
P value
|
Rate ratiob
|
P value
|
|---|
|
IRLOS, hours, mean (SD)
|
91.5 (57.8)
|
93.2 (60.8)
|
0.823
|
1.002 (0.844–1.191)
|
0.979
|
|
Total LOS, hours, mean (SD)
|
98.5 (77.0)
|
101.2 (72.1)
|
0.785
|
1.018 (0.861–1.204)
|
0.833
|
|
Total inpatient cost, 2012 US$, mean (SD)a
|
9641 (6683)
|
9083 (5855)
|
0.509
|
0.940 (0.803–1.101)
|
0.442
|
- IRLOS infection-related length of stay, LOS length of stay, MVAS multivariate analytic sample, PAS primary analytic sample, SD standard deviation
- aWholesale acquisition cost estimates using “waste” algorithm
- bRate ratio reflects effect of vancomycin relative to daptomycin on outcome of interest. Ratios reported as mean (95 % confidence interval)
