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Table 3 Kappa statistics and positive and negative samples detected by rapid tests using saliva (3) and whole blood (1) samples compared to results obtained using respective serum samples by enzyme immunoassay ETI-MAK-4®, according to the characteristics of the population under analysis

From: Evaluating HBsAg rapid test performance for different biological samples from low and high infection rate settings & populations

Profile/Manufactory – Biological specimen

TP

FN

TN

FP

K

Group I

 Vikia HBsAg® - SALIVA

6

76

101

2

5.92 % (0.00–21.8)

 Imuno-Rápido HBsA® - SALIVA

33

49

101

2

40.68 % (26.82–54.54)

 Teste rápido HBsAg®- SALIVA

2

80

101

2

0.55 % (0.00–16.61)

 Vikia HBsAg® - WHOLE BLOOD

18

10

80

0

72.73 % (56.63–88.83)

Group II

 Vikia HBsAg® - SALIVA

0

2

153

5

a

 Imuno-Rápido HBsA® - SALIVA

1

1

155

3

32.2 % (0.00– 97.8)

 Teste rápido HBsAg® - SALIVA

0

2

158

0

a

 Vikia HBsAg® - WHOLE BLOOD

0

3

763

1

a

Group III

 Vikia HBsAg® - SALIVA

0

4

153

0

a

 Imuno-Rápido HBsA® - SALIVA

0

4

149

4

a

 Teste rápido HBsAg® - SALIVA

0

4

150

3

a

 Vikia HBsAg® - WHOLE BLOOD

4

2

387

0

79.75 % (51.76–100.00)

Overall

 Vikia HBsAg® - SALIVA

6

82

407

7

7.72 % (0,00–25,11)

 Imuno-Rápido HBsA® - SALIVA

34

54

405

9

45.65 % (33.1–58.2)

 Teste rápido HBsAg® - SALIVA

2

86

409

5

1.67 % (0.00–19.95)

 Vikia HBsAg® - WHOLE BLOOD

22

15

1230

1

72.72 % (59.44–86.00)

  1. Legend: TP True positive, FN False negative, TN True negative, FP False positive, k kappa statistics, n number of observations (biological samples), CI confidence interval
  2. anot amenable to calculation