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Table 4 Mean seasonal RSV-attributable burden of GP episodes, hospitalizations and deaths by risk group*, in individuals 65+ years of age; United Kingdom 1995-2009

From: Modelling estimates of the burden of Respiratory Syncytial virus infection in adults and the elderly in the United Kingdom

 

GP episodes

Hospitalisations

Deaths

 

Episodes/100,000 population (range)

N

Hospitalisations/100,000 population (range)

N

Deaths/100,000 population (range)

N

Respiratory disease

1946 (1400–2267)

175,070

156 (119–192)

14,039

88 (64–119)

7,915

Low risk

1335 (963–1560)

120,123

60 (46–74)

5,380

60 (41–84)

5,425

High risk

2697 (1864–3189)

242,616

265 (194–314)

23,872

121 (97–156)

10,915

Acute upper respiratory disease

544 (420–681)

48,900

-

-

-

-

Low risk

457 (349–566)

41,150

-

-

-

-

High risk

644 (492–798)

57,961

-

-

-

-

Pneumonia and Influenza

154 (88–219)

13,814

49 (32–66)

4,367

66 (47–89)

5,894

Low risk

109 (63–153)

9,807

28 (21–37)

2,559

53 (37–72)

4,729

High risk

211 (115–312)

19,025

70 (47–95)

6,322

81 (62–107)

7,307

Bronchitis/ Bronchiolitis

1328 (954–1545)

119,449

46 (34–55)

4,114

3 (2–4)

277

Low risk

849 (597–984)

76,385

30 (22–36)

2,683

1 (0–1)

75

High risk

1908 (1336–2221)

171,650

64 (46–75)

5,749

6 (4–7)

520

COPD

110 (59–166)

9,921

59 (43–70)

5,352

24 (19–30)

2,187

Low risk

0 (0–0)

2

0 (0–0)

0

0 (0–0)

0

High risk

259 (123–420)

23,306

127 (88–153)

11,464

53 (39–63)

4,807

Cardiorespiratory

-

-

112 (81–131)

10,086

113 (90–145)

10,147

Low risk

-

-

55 (43–69)

4,990

60 (40–83)

5,365

High risk

-

-

177 (117–229)

15,964

177 (129–209)

15,909

  1. N = Seasonal number of specified RSV-attributable events in the UK. Note that the attributions for the full 65+ population are not equal to the sum of the attributions in 65–74 and 75+ year age groups in Table 3 due to separately run models
  2. Rate = per 100,000 population
  3. Range = range of estimates per season
  4. GP = general practice, COPD = chronic obstructive pulmonary disease
  5. *Risk group defined according to the chronic conditions indicative of risk for severe influenza as per UK recommendation for influenza vaccination. These include COPD; cardiovascular, central nervous system, renal and liver disorders; diabetes; immunosuppressive conditions or stroke