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Table 4 Mean seasonal RSV-attributable burden of GP episodes, hospitalizations and deaths by risk group*, in individuals 65+ years of age; United Kingdom 1995-2009

From: Modelling estimates of the burden of Respiratory Syncytial virus infection in adults and the elderly in the United Kingdom

  GP episodes Hospitalisations Deaths
  Episodes/100,000 population (range) N Hospitalisations/100,000 population (range) N Deaths/100,000 population (range) N
Respiratory disease 1946 (1400–2267) 175,070 156 (119–192) 14,039 88 (64–119) 7,915
Low risk 1335 (963–1560) 120,123 60 (46–74) 5,380 60 (41–84) 5,425
High risk 2697 (1864–3189) 242,616 265 (194–314) 23,872 121 (97–156) 10,915
Acute upper respiratory disease 544 (420–681) 48,900 - - - -
Low risk 457 (349–566) 41,150 - - - -
High risk 644 (492–798) 57,961 - - - -
Pneumonia and Influenza 154 (88–219) 13,814 49 (32–66) 4,367 66 (47–89) 5,894
Low risk 109 (63–153) 9,807 28 (21–37) 2,559 53 (37–72) 4,729
High risk 211 (115–312) 19,025 70 (47–95) 6,322 81 (62–107) 7,307
Bronchitis/ Bronchiolitis 1328 (954–1545) 119,449 46 (34–55) 4,114 3 (2–4) 277
Low risk 849 (597–984) 76,385 30 (22–36) 2,683 1 (0–1) 75
High risk 1908 (1336–2221) 171,650 64 (46–75) 5,749 6 (4–7) 520
COPD 110 (59–166) 9,921 59 (43–70) 5,352 24 (19–30) 2,187
Low risk 0 (0–0) 2 0 (0–0) 0 0 (0–0) 0
High risk 259 (123–420) 23,306 127 (88–153) 11,464 53 (39–63) 4,807
Cardiorespiratory - - 112 (81–131) 10,086 113 (90–145) 10,147
Low risk - - 55 (43–69) 4,990 60 (40–83) 5,365
High risk - - 177 (117–229) 15,964 177 (129–209) 15,909
  1. N = Seasonal number of specified RSV-attributable events in the UK. Note that the attributions for the full 65+ population are not equal to the sum of the attributions in 65–74 and 75+ year age groups in Table 3 due to separately run models
  2. Rate = per 100,000 population
  3. Range = range of estimates per season
  4. GP = general practice, COPD = chronic obstructive pulmonary disease
  5. *Risk group defined according to the chronic conditions indicative of risk for severe influenza as per UK recommendation for influenza vaccination. These include COPD; cardiovascular, central nervous system, renal and liver disorders; diabetes; immunosuppressive conditions or stroke