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Table 3 Mean seasonal RSV-attributable burden of GP episodes, hospital admissions and deaths due to respiratory disease among adults by age group; United Kingdom 1995-2009

From: Modelling estimates of the burden of Respiratory Syncytial virus infection in adults and the elderly in the United Kingdom

 

GP episodes

Hospitalisations

Deaths

Age (years)

Episodes/100,000 population (range)

N

% of events attributable to RSV**

RSV:influenza

ratio†

Hospitalisations/100,000 population (range)

N

% of events attributable to RSV**

RSV:influenza ratio†

Deaths/100,000 population (range)

N

% of events attributable to RSV**

RSV:influenza ratio†

Respiratory disease

18-49

677 (443–850)

176534

3.3

0.6:1

4 (3–5)

1033

1.4

0.3:1

1 (0–1)

144

4.2

0.8:1

50-64

1325 (928–1542)

136469

6.1

1.1:1

30 (22–36)

3067

5.2

0.8:1

6 (5–7)

656

5.9

0.9:1

65-74

1742 (1259–2038)

86201

6.6

1.6:1

86 (62–101)

4236

5.8

0.8:1

29 (21–33)

1416

5.7

0.9:1

75+

2175 (1554–2516)

88043

7.5

1.6:1

234 (180–291)

9463

6.8

0.9:1

155 (108–213)

6266

5.9

0.7:1

Acute upper respiratory disease

18-49

394 (261–489)

102728

3.9

0.8:1

-

-

-

-

-

-

-

-

50-64

590 (430–696)

60757

7.8

1.7:1

-

-

-

-

-

-

-

-

65-74

557 (433–701)

27580

8.4

2.5:1

-

-

-

-

-

-

-

-

75+

528 (407–659)

21372

10.1

2.4:1

-

-

-

-

-

-

-

-

Pneumonia and Influenza

18-49

51 (17–97)

13217

5.8

0.1:1

2 (2–3)

615

5.8

0.6:1

0 (0–1)

103

5.9

0.8:1

50-64

88 (40–145)

9031

10.4

0.2:1

7 (5–9)

736

7.2

1.0:1

4 (3–5)

391

7.3

0.9:1

65-74

116 (66–167)

5755

13.6

0.4:1

20 (15–26)

987

7.3

1.0:1

17 (12–20)

821

6.7

0.8:1

75+

196 (112–279)

7944

11.2

0.6:1

80 (51–109)

3238

7.7

1.0:1

121 (86–164)

4884

7.1

0.7:1

Bronchitis/ Bronchiolitis

18-49

229 (163–264)

59799

6.0

0.7:1

2 (1–2)

444

4.3

0.5:1

0 (0–0)

4

6.2

0.6:1

50-64

653 (458–759)

67269

9.7

1.2:1

7 (5–9)

764

8.3

0.7:1

0 (0–1)

43

17.2

1.0:1

65-74

1088 (776–1257)

53839

11.0

1.8:1

19 (14–22)

952

9.1

0.7:1

1 (1–2)

66

12.6

1.0:1

75+

1594 (1147–1858)

64540

12.3

1.8:1

75 (56–91)

3037

10.6

0.8:1

5 (3–7)

204

10.2

0.8:1

COPD

18-49

23 (14–31)

6034

1.2

1.7:1

0 (0–0)

0

0.0

0:1

0 (0–0)

15

3.8

0.7:1

50-64

77 (49–100)

7943

2.7

2.2:1

14 (10–17)

1484

5.8

0.8:1

3 (2–4)

296

8.9

1.1:1

65-74

136 (72–206)

6734

2.7

2.9:1

45 (32–52)

2229

6.5

0.9:1

14 (9–17)

685

7.5

0.9:1

75+

82 (44–121)

3300

1.7

1.4:1

75 (55–88)

3052

7.4

1.2:1

36 (27–48)

1456

6.5

0.8:1

Cardiorespiratory

18-49

-

-

 

-

1 (1–3)

376

0.4

0.1:1

1 (1–1)

213

2.8

1:1

50-64

-

-

 

-

18 (12–22)

1837

1.3

0.5:1

8 (6–10)

859

3.4

0.9:1

65-74

-

-

 

-

56 (39–67)

2780

1.6

0.6:1

37 (25–44)

1826

3.5

0.9:1

75+

-

-

 

-

174 (126–204)

7042

2.3

0.7:1

198 (155–259)

8028

4.1

0.8:1

Antibiotic prescriptions

18-49

610 (442–715)

159223

2.6

0.7:1

-

-

-

-

-

-

-

-

50-64

1449 (1081–1750)

149229

5.3

1.4:1

-

-

-

-

-

-

-

-

65-74

1999 (1556–2520)

98921

6.0

2:1

-

-

-

-

-

-

-

-

75+

2261 (1809–2938)

91535

6.3

2.1:1

-

-

-

-

-

-

-

-

  1. N = Seasonal number of specified RSV-attributable events in the UK
  2. Proportion = per 100,000 population
  3. Range = range of estimates per season
  4. GP = general practice, COPD = chronic obstructive pulmonary disease
  5. *Outcomes refer to the ‘Primary’ cause for hospitalisation for HES, or as the ‘Any mention’ cause of death for ONS. For the GPRD data there is no ordered listing or ranking of diagnostic codes
  6. **% of RSV-attributable events among all events due to outcome
  7. † ratio of proportions/100,000 RSV/[influenza A + B]