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Table 3 Predictors of risk of recurrent SSTI in univariate and multivariate Cox regression models

From: Recurrent skin and soft tissue infections in HIV-infected patients during a 5-year period: incidence and risk factors in a retrospective cohort study

Factor Univariate HR p-value Multivariate HR (Final model) p-value
(95 % CI)   (95 % CI)
HAART 0.67 (0.31–1.44) 0.30   
Trimethoprim-sulfamethoxazole 0.73 (0.28–1.91) 0.52   
Azithromycin 1.38 (0.48–3.98) 0.55   
Age (cont) 0.99 (0.96–1.03) 0.71   
STD (any) 1.06 (0.49–2.27) 0.88   
Chlamydia 1.18 (0.16–8.77) 0.87   
Gonorrhea 4.96 (0.65–37.7) 0.12   
Syphilis 0.49 (0.07–3.59) 0.48   
Human papilloma virus (clinical) 1.58 (0.60–4.17) 0.35   
Human papilloma virus (Pap) 1.12 (0.43–2.92) 0.82   
Trichomonas 0.45 (0.06–3.33) 0.44   
Catheter 4.62 (1.08–19.7) 0.04 6.50 (1.47–28.7) 0.01
Medicaid 0.64 (0.30–1.37) 0.25   
End stage renal disease 0.70 (0.16–2.93) 0.62   
Cancer 0.51 (0.07–3.73) 0.51   
Diabetes 1.03 (0.39–2.69) 0.96   
Hepatitis B 1.27 (0.38–4.20) 0.69   
Hepatitis C 0.91 (0.32–2.61) 0.86   
Incarceration 0.22 (0.03–1.65) 0.14   
Other chronic liver disease 2.89 (1.00–8.35) 0.05 3.43 (1.02-11.5) 0.05
Men who have sex with men 0.81 (0.36–1.81) 0.60   
IVDU 2.41 (0.98–5.91) 0.06 2.80 (1.02-7.65) 0.05
Male 0.87 (0.42–1.79) 0.71   
African-American race 0.34 (0.11–1.00) 0.05 0.12 (0.03-0.41) <0.01
Chronic skin disease: Any 1.36 (0.66–2.79) 0.41   
Psoriasis 0.46 (0.06–3.39) 0.45   
Lymphedema 4.12 (1.24–14.1) 0.02   
CD4     
100+ Reference    
<100 1.13 (0.39–3.24) 0.83   
Viral load     
<1000 Reference   Reference  
1000+ 1.58 0.22 2.21 (0.99–4.94) 0.05
Initial SSTI type     
Abscess Reference    
Furuncle 0.26 (0.03–1.91) 0.19   
Cellulitis 0.66 (0.28–1.55) 0.34   
Incision and drainage performed on initial SSTI 1.69 (0.82–3.47) 0.15   
Initial SSTI S. aureus 2.10 (0.93–4.72) 0.07   
Initial SSTI MRSA 2.21 (0.90–5.40) 0.08