Table 5 Predictors of treatment failure in HIV-positive adults on MDR-TB treatment at Sizwe Tropical Disease Hospital, Johannesburg

ART regimen

 After

1.00

1.00

 Prior

1.01 (0.47–2.15)

0.988

0.80 (0.35–1.84)

0.606

Age groups

 18–45

1.00

 46–76

0.79 (0.27–2.28)

0.662

BMI

0.97 (0.87–1.07)

0.547

1.01 (0.94–1.09)

0.766

Haemoglobin (g/dl)

 Severe Anaemia (<7.0)

2.69 (0.78–9.30)

0.117

4.72 (1.47–15.08)

0.009*

 Moderate Anaemia (7.0–9.99)

1.09 (0.46–2.57)

0.839

0.97 (0.40–2.34)

0.944

 Mild Anaemia (10–10.99)

0.43 (0.10–1.87)

0.260

0.25 (0.03–1.82)

0.172

 Normal (≥11)

1.00

1.00

Infiltrative changes

 No

1.00

 Yes

1.01 (0.14–7.47)

0.990

Cavitary changes

 No

1.00

1.00

 Yes

1.81 (0.85–3.87)

0.125

2.14 (0.96–4.78)

0.064

Fibrotic changes

 No

1.00

 Yes

1.36 (0.41–4.50)

0.620

Comorbidity

 No

1.00

1.00

 Yes

1.79 (0.72–4.41)

0.207

2.39 (1.05–5.43)

0.039*

Adverse events

 No

1.00

1.00

 Yes

0.54 (0.24–1.23)

0.142

0.48 (0.21–1.09)

0.080

Regimen type at baseline

 Standardised

1.00

1.00

 Modified individualised

2.48 (1.18–5.20)

0.016*

2.15 (0.98–4.71)

0.056