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Table 3 Patient characteristics and other factors evaluated for their associations with serological outcomes after syphilis therapy

From: A systematic review of syphilis serological treatment outcomes in HIV-infected and HIV-uninfected persons: rethinking the significance of serological non-responsiveness and the serofast state after therapy

First Author

PatientAge

Patient Gender

Baseline nontrepo-nemal titers

Stage of syphilis infection

History of prior syphilis

Trepo-nemal IgM

Syphilis treatment regimen

HIV coinfection

CD4 cell count

HIV viral load

Antiretroviral therapy

Dionne-Odom

 

+

+

+

   

   

Fiumara

  

+

        

Ghanem (2007) [23]

   

   

+

   

Goemen

       

   

Knaute

   

+

   

   

Li

  

+

+

 

+

     

Long

  

+

   

   

Manavi

 

+

 

+

 

   

Reidner

+

+

  

   

Rolfs

    

 

+

   

Romanowski

+

+

+

      

Seña

+

 

+

+

 

    

Tittes

+

+

  

+

   

Tong

+

+

+

+

       

Ghanem (2008) [24]

+

     

H

+

+

Jinno

 

+

+

 

H

+

Malone

       

H

  

Tsai

+

   

 

H

Wu

 

+

   

H

Yang

  

+

+

 

+

H

  1. H indicates that the study included HIV-infected participants only
  2. + indicates a significant association in multivariate analyses between the variable and serological outcomes after therapy
  3. – indicates that a significant association was not identified between the variable and serological outcomes after therapy