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Table 4 Proportion of S. pneumoniae and H. influenzae (%) with reduced antimicrobial susceptibility. Bacteria isolated in first half of study (1996–2000) were compared to those from the second half of study (2001–2005). Yates chi-square test was used to compare the proportion of strains that were resistant in the first half of the study period (1996–2000) with that in the second half of the study period (2001–2005)

From: Streptococcus pneumoniae and Haemophilus influenzae in paediatric meningitis patients at Goroka General Hospital, Papua New Guinea: serotype distribution and antimicrobial susceptibility in the pre-vaccine era

  1996–2000 2001–2005 P value
S. pneumoniae    
 Penicillin 29/116 (25.0) 9/61 (14.8) 0.12
 Chloramphenicol 1/115 (0.9) 3/61 (4.9) 0.09
 Cotrimoxazole 9/116 (7.8) 6/60 (10.0) 0.64
 Tetracycline 2/69 (2.9) 2/27 (7.4) 0.32
H. influenzae    
 Ampicillin 27/104 (26.0) 27/58 (46.6) 0.01
 Chloramphenicol 27/104 (26.0) 24/58 (41.4) 0.04
 Cotrimoxazole 35/104 (33.7) 28/58 (48.3) 0.07