From: Risk factors for severe hand foot mouth disease in Singapore: a case control study
Cases (n = 24) | Controls (n = 48) | p valuea | |
---|---|---|---|
GCS < 15 at presentation | 7 (29 %) | 0 (0 %) | <0.001 |
Deterioration in GCSa | 4 (17 %) | 0 (0 %) | 0.010 |
Seizure on arrival | 6 (25 %) | 0 (0 %) | 0.001 |
Altered mentation | 11 (46 %) | 0 (0 %) | <0.001 |
Poor peripheral perfusion | 8 (33 %) | 0 (0 %) | <0.001 |
Distribution of rash and presence of ulcers (N = 23 vs 48) | |||
Typical hands and feet rash and oral ulcers | 15 (63 %) | 41 (85 %) | 0.037 |
Absence of oral ulcers | 6 (25 %) | 4 (8 %) | 0.066 |
Meningeal irritation | 4 (17 %) | 0 (0 %) | 0.010 |