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Table 3 Clinical signs at presentation

From: Risk factors for severe hand foot mouth disease in Singapore: a case control study

  Cases (n = 24) Controls (n = 48) p valuea
GCS < 15 at presentation 7 (29 %) 0 (0 %) <0.001
Deterioration in GCSa 4 (17 %) 0 (0 %) 0.010
Seizure on arrival 6 (25 %) 0 (0 %) 0.001
Altered mentation 11 (46 %) 0 (0 %) <0.001
Poor peripheral perfusion 8 (33 %) 0 (0 %) <0.001
Distribution of rash and presence of ulcers (N = 23 vs 48)    
 Typical hands and feet rash and oral ulcers 15 (63 %) 41 (85 %) 0.037
 Absence of oral ulcers 6 (25 %) 4 (8 %) 0.066
Meningeal irritation 4 (17 %) 0 (0 %) 0.010
  1. aAny drop in GCS