Skip to main content

Table 1 Demographic data and presenting history

From: Risk factors for severe hand foot mouth disease in Singapore: a case control study

  Cases (n = 24) Controls (n = 48) OR (95 % CI) P valuea
Demographics     
Age (year) median (IRQ) 3.0 (1.5;5.5) 2.5 (1;5.5) 1.04 (0.70;1.55) 0.848
Female 15 (63 %) 26 (54 %) 0.72 (0.27;1.92) 0.506
Presenting History     
Level of fever (°C) (N = 23 vs 42) median (IQR) 39 (38.7;39.4) 39 (38.5;39.5) 1.06 (0.49;2.25) 0.888
Temperature ≥ 39 °C 17 (74 %) 24 (57 %) 2.19 (0.69;6.96) 0.183
Temperature < 39 °C 6 (26 %) 18 (43 %)   
Duration of fever (days) 3.3 (2.0) 2.4 (1.6) 1.27 (0.97;1.67) 0.077
Contact history (N = 23 vs 48) 13 (57 %) 20 (42 %) 1.94 (0.65;5.79) 0.236
Vomiting 10 (42 %) 16 (33 %) 1.42 (0.52;3.86) 0.494
Symptoms of hypoperfusionc 11 (46 %) 8 (17 %) NC 0.012b
Seizure 12 (50 %) 1 (2 %) NC <0.001b
Altered mentation 8 (33 %) 3 (6 %) 13.11 (1.61;106.60) 0.016
  1. NC non-computable
  2. afrom conditional logistic regression
  3. bfrom Fisher’s exact test
  4. cas characterized by lethargy, syncope or reported cool extremities