Table 3 Univariate and multivariate analysis of selected clinical and radiographic variables
Univariate analysis | Multivariate analysis | |||||
|---|---|---|---|---|---|---|
Risk Factor | Category | Mycobacterial lung disease (52) | Lung Cancer (139) | P-value | OR for lung cancer vs mycobacterial lung disease (95 % CI)d | P-value |
Smoking status | Current | 4 (7.7) | 38 (27.3) | 0.005 | 4.4 (1.2–15.6) | 0.04 |
Former | 33 (63.5) | 78 (56.1) | 2.7 (1.1–6.8) | |||
Never | 15 (28.8) | 23 (16.5) | 1 | |||
Cumulative smokinga | Median (IQR) | 23 (5–39) | 40 (30–58) | <0.0001 | ||
Body mass index | Mean (STD) | 25.1 (4.9) | 27.3 (5.3) | 0.01 | ||
History of cancer | No | 26 (50.0) | 103 (74.1) | 0.003 | ||
Yes | 26 (50.0) | 36 (25.9) | ||||
Number of tumorsb | 0 | 26 (50.0) | 103 (74.1) | 0.004 | ||
1 | 23 (44.2) | 29 (20.9) | ||||
2+ | 3 (5.8) | 7 (5.0) | ||||
Active cancerc | No | 20 (76.9) | 28 (77.8) | 1.0 | ||
Yes | 6 (23.1) | 8 (22.2) | ||||
Lesion type | Nodule (<3 cm) | 43 (82.7) | 67 (48.2) | <0.0001 | 0.5 (0.2–1.2) | 0.12 |
Mass (≥3 cm) | 9 (17.3) | 72 (51.8) | 1 | |||
SUV max | Median (IQR) | 6.5 (4.0–8.7) | 9.5 (4.9–14.5) | 0.001 | ||
Per unit increase | 1.1 (1.0–1.2) | 0.04 | ||||
Tree-in-bud opacities in CT | No | 43(82.7) | 139 (100) | <0.0001 | 1 | 0.05 |
Yes | 9 (17.3) | 0 | 0.04 (0.0–1.0) | |||