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Table 3 Univariate and multivariate analysis of selected clinical and radiographic variables

From: Clinical and radiographic differentiation of lung nodules caused by mycobacteria and lung cancer: a case–control study

  Univariate analysis Multivariate analysis
Risk Factor Category Mycobacterial lung disease (52) Lung Cancer (139) P-value OR for lung cancer vs mycobacterial lung disease (95 % CI)d P-value
Smoking status Current 4 (7.7) 38 (27.3) 0.005 4.4 (1.2–15.6) 0.04
  Former 33 (63.5) 78 (56.1)   2.7 (1.1–6.8)  
  Never 15 (28.8) 23 (16.5)   1  
Cumulative smokinga Median (IQR) 23 (5–39) 40 (30–58) <0.0001   
Body mass index Mean (STD) 25.1 (4.9) 27.3 (5.3) 0.01   
History of cancer No 26 (50.0) 103 (74.1) 0.003   
  Yes 26 (50.0) 36 (25.9)    
Number of tumorsb 0 26 (50.0) 103 (74.1) 0.004   
  1 23 (44.2) 29 (20.9)    
  2+ 3 (5.8) 7 (5.0)    
Active cancerc No 20 (76.9) 28 (77.8) 1.0   
  Yes 6 (23.1) 8 (22.2)    
Lesion type Nodule (<3 cm) 43 (82.7) 67 (48.2) <0.0001 0.5 (0.2–1.2) 0.12
  Mass (≥3 cm) 9 (17.3) 72 (51.8)   1  
SUV max Median (IQR) 6.5 (4.0–8.7) 9.5 (4.9–14.5) 0.001   
  Per unit increase     1.1 (1.0–1.2) 0.04
Tree-in-bud opacities in CT No 43(82.7) 139 (100) <0.0001 1 0.05
  Yes 9 (17.3) 0   0.04 (0.0–1.0)  
  1. Data are presented as No. (%) unless otherwise specified. Abbreviations: BMI Body Mass Index, OR Odds Ratio, CI Confidence Interval, SUV Max Maximum Standardized Uptake Value
  2. aExpressed in pack-years
  3. bIn patients with a history of cancer
  4. cOf those patients with a history of cancer
  5. dResults presented as adjusted OR