TY - JOUR AU - Cassol, Edana AU - Rossouw, Theresa AU - Malfeld, Susan AU - Mahasha, Phetole AU - Slavik, Tomas AU - Seebregts, Chris AU - Bond, Robert AU - du Plessis, Johannie AU - Janssen, Carl AU - Roskams, Tania AU - Nevens, Frederik AU - Alfano, Massimo AU - Poli, Guido AU - van der Merwe, Schalk W. PY - 2015 DA - 2015/10/17 TI - CD14+ macrophages that accumulate in the colon of African AIDS patients express pro-inflammatory cytokines and are responsive to lipopolysaccharide JO - BMC Infectious Diseases SP - 430 VL - 15 IS - 1 AB - Intestinal macrophages are key regulators of inflammatory responses to the gut microbiome and play a central role in maintaining tissue homeostasis and epithelial integrity. However, little is known about the role of these cells in HIV infection, a disease fuelled by intestinal inflammation, a loss of epithelial barrier function and increased microbial translocation (MT). SN - 1471-2334 UR - https://doi.org/10.1186/s12879-015-1176-5 DO - 10.1186/s12879-015-1176-5 ID - Cassol2015 ER -