Table 2 Summary of VLPs investigated in this study
VLP | Accession number | AA position in p24 (Gag)a | AA in wt VLP | AA change introduced | HIV diagnostic test with low sensitivity for wt |
|---|---|---|---|---|---|
pBV8-B | KJ689249 | 16 (148) | T | S | Siemens Enzygnost Integral II/4 |
pBV59-F2 | KJ689286 | 16 (148) | T | S | Siemens Enzygnost Integral II/4 |
pBV11-B | KJ689251 | 16 (148) | S | T | N/A – control VLP |
pBV43-D | KJ689277 | 170 (302) | R | K | bioMérieux VIDAS HIVp24 II |
pBV60-D | KJ689287 | 170 (302) | R | K | bioMérieux VIDAS HIVp24 II |
pBV42-12BF | KJ689276 | 170 (302) | N | K | bioMérieux VIDAS HIVp24 II |
pBV38-D | KJ689274 | 170 (302) | K | R | N/A – control VLP |