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Table 2 Summary of VLPs investigated in this study

From: Impact of naturally occurring amino acid variations on the detection of HIV-1 p24 in diagnostic antigen tests

VLP Accession number AA position in p24 (Gag)a AA in wt VLP AA change introduced HIV diagnostic test with low sensitivity for wt
pBV8-B KJ689249 16 (148) T S Siemens Enzygnost Integral II/4
pBV59-F2 KJ689286 16 (148) T S Siemens Enzygnost Integral II/4
pBV11-B KJ689251 16 (148) S T N/A – control VLP
pBV43-D KJ689277 170 (302) R K bioMérieux VIDAS HIVp24 II
pBV60-D KJ689287 170 (302) R K bioMérieux VIDAS HIVp24 II
pBV42-12BF KJ689276 170 (302) N K bioMérieux VIDAS HIVp24 II
pBV38-D KJ689274 170 (302) K R N/A – control VLP
  1. AA amino acid, wt wildtype, N/A not applicable as these VLPs were used as controls
  2. ain HXB2 reference sequence; accession number in NCBI GenBank