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Table 1 Summary of typhoid fever vaccines [6, 1316]

From: Typhoid fever cases in the U.S. military

Typhoid vaccine Route 3-year efficacy Booster Adverse reactions
Local Systemic
Vi Polysaccharide Parenteral 30–70 % 2 years 10–40 % 2 %
Live Ty21a Oral 34–58 % 5 years NA <1 %
Parenteral heat-phenol inactivated Parenteral 51–77 % 3 years 10–50 % 10–20 %
Acetone-inactivated Parenteral 75–94 % Not applicable 10–50 % 10–20 %