Skip to main content

Table 2 Laboratory test results. Laboratory parameters on admission of 153 hospitalized adults with dengue by dengue severity according to the WHO’s 2009 definition

From: Identification of clinical factors associated with severe dengue among Thai adults: a prospective study

Characteristics Severe dengue (n = 21) Non-severe dengue (n = 132) p-value
# (%) # (%)
Confirmation tests for dengue    
Known dengue RT-PCR (n = 88)    0.765
 Serotypes 1 or 4 4 (19.0) 25 (18.9)  
 Serotypes 2 or 3 11 (52.4) 48 (36.4)  
Known serological response to infection (n = 144)    0.551
 Primary dengue infection 1 (4.8) 4 (3.0)  
 Secondary dengue infection 20 (95.2) 119 (90.2)  
Complete blood counts    
Hemoglobin, median (IQR), g/dL 14.0 (12.5–16.6) 13.8 (12.8–14.9) 0.627
Hematocrit, median (IQR), % 41.7 (36.7–48.5) 41.1 (38.3–44.4) 0.934
WBC, median (IQR), ×103 cells per μL 4.7 (2.4–10.5) 3.1 (2.3–4.6) 0.034
Absolute band form, median (IQR), cells per μL 188 (87–372) 142 (60–666) 0.237
Absolute PMN, median (IQR), cells per μL 2320 (1210–4126) 1620 (873–2264) 0.055
Absolute LYM, median (IQR), cells per μL 940 (405–2011) 758 (546–1126) 0.509
Absolute ALYM, median (IQR), cells per μL 684 (108–1370) 138 (68–379) 0.011
Platelet counts, median (IQR) × 103 per μL 56.0 (12.0–71.0) 85.0 (56.0–136.2) <0.001
Categorical data    
Hematocrit    0.928
  ≤ 2 % above reference range 7 (33.3) 49 (37.1)  
  > 2 % above reference range 14 (66.7) 83 (62.9)  
Absolute band form    1.000
  ≤ 250 cells per μL 15 (71.4) 97 (73.5)  
  > 250 cells per μL 6 (28.6) 35 (26.5)  
Absolute PMN    0.422
  < 1500 cells per μL 7 (33.3) 60 (45.5)  
  ≥ 1500 cells per μL 14 (66.7) 72 (54.5)  
Absolute LYM    0.036
  ≤ 2000 cells per μL 16 (76.2) 122 (92.4)  
  > 2000 cells per μL 5 (23.8) 10 (7.6)  
Absolute ALYM    0.002
  ≤ 300 cells per μL 8 (38.1) 99 (75.0)  
  > 300 cells per μL 13 (61.9) 33 (25.0)  
Platelet counts    0.031
  ≤ 100 × 103 per μL 18 (85.7) 77 (58.3)  
  > 100 × 103 per μL 3 (14.3) 55 (41.7)  
Blood chemistries    
Creatinine, median (IQR), mg/dL 0.8 (0.6–1.1) 0.8 (0.6–1.0) 0.739
Lactate level, median (IQR), mmol/L 2.7 (1.7–3.1) 1.4 (1.2–1.8) <0.001
Albumin, median (IQR), g/dL 3.7 (3.2–4.3) 4.3 (4.0–4.5) <0.001
AST, median (IQR), IU/L 219 (94–692) 76 (37–158) <0.001
ALT, median (IQR), IU/L 100 (61–346) 47 (18–106) 0.003
Categorical data    
Lactate level    <0.001
  < 2.0 mmol/L 7 (33.3) 111 (84.1)  
  ≥ 2.0 mmol/L 14 (66.7) 21 (15.9)  
Albumin    <0.001
  < 3.5 g/dL 13 (61.9) 128 (97.0)  
  ≥ 3.5 g/dL 8 (38.1) 4 (3.0)  
AST    0.017
  ≤ 120 IU/L 7 (33.3) 84 (63.6)  
  > 120 IU/L 14 (66.7) 48 (36.4)  
ALT    0.032
  ≤ 120 IU/L 11 (52.4) 102 (77.3)  
  > 120 IU/L 10 (47.6) 30 (22.7)  
  1. Abbreviations: RT-PCR reverse-transcriptase polymerase chain reaction, IQR interquartile range, WBC white blood cell counts, PMN neutrophils, LYM lymphocytes, ALYM atypical lymphocytes, AST aspartate aminotranferase, ALT alanine aminotransferase