Table 1 Patient characteristics. Baseline characteristics and clinical parameters at admission of 153 hospitalized adults with either severe or non-severe dengue according to the WHO’s 2009 definition
Characteristics | Severe dengue (n = 21) | Non-severe dengue (n = 132) | p-value |
|---|---|---|---|
# (%) | # (%) | ||
Baseline characteristics | Â | Â | Â |
Age | Â | Â | 0.004 |
  ≤ 40 years | 12 (57.1) | 113 (85.6) |  |
  > 40 years | 9 (42.9) | 19 (14.4) |  |
Gender | Â | Â | 0.771 |
 Male | 10 (47.6) | 71 (53.8) |  |
 Female | 11 (52.4) | 61 (46.2) |  |
Residential area | Â | Â | 1.000 |
 Bangkok | 18 (85.7) | 109 (82.6) |  |
 Outside Bangkok | 3 (14.3) | 23 (17.4) |  |
Medication before admission | Â | Â | Â |
 Acetaminophen | 20 (95.2) | 123 (93.2) | 1.000 |
 NSAIDs or COX II inhibitors | 6 (28.6) | 13 (9.8) | 0.027 |
Clinical parameters | Â | Â | Â |
Vital signs | Â | Â | Â |
 Temperature, median (IQR), °C | 37.8 (37.0–39.0) | 38.4 (37.8–39.2) | 0.162 |
 HR, median (IQR), beats/min | 82 (68–90) | 79 (66–88) | 0.176 |
 MAP, median (IQR), mmHg | 83 (70–92) | 86 (78–92) | 0.561 |
 PP, median (IQR), mmHg | 32 (26–45) | 38 (33–45) | 0.058 |
History and physical examinations | Â | Â | Â |
 Myalgia | 20 (95.2) | 120 (90.9) | 1.000 |
 Lethargy | 19 (90.5) | 101 (76.5) | 0.251 |
 Headache | 18 (87.5) | 113 (85.6) | 1.000 |
 Fever ≥4 days | 17 (81.0) | 84 (63.6) | 0.191 |
 Tourniquet test positive | 16 (76.2) | 111 (84.1) | 0.359 |
 RR ≥24 breaths/min | 15 (71.4) | 112 (84.8) | 0.206 |
 Mucosal bleeding | 14 (66.7) | 48 (36.4) | 0.017 |
 Skin bleeding | 13 (61.9) | 28 (21.2) | <0.001 |
 Liver span > 15 cm | 12 (57.1) | 19 (14.4) | <0.001 |
 Retro-orbital pain | 11 (52.4) | 90 (68.2) | 0.241 |
 Decrease breath sound | 11 (52.4) | 6 (4.5) | <0.001 |
 Arthralgia | 10 (47.6) | 37 (28.0) | 0.120 |
 Rash | 10 (47.6) | 61 (46.2) | 1.000 |
 Abdominal pain | 9 (42.9) | 53 (40.2) | 1.000 |
 Persistent vomiting | 9 (42.9) | 15 (11.4) | 0.001 |
 Diarrhea | 5 (23.8) | 44 (33.3) | 0.537 |