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Table 5 Univariate & multivariate analysis of risk factors for mortality in all necrotizing fasciitis patients

From: Necrotizing fasciitis in patients with diabetes mellitus: clinical characteristics and risk factors for mortality

Variable Univariate analysis Multivariate analysis   
  OR(95 % CI) P value OR(95 % CI) P value
Age 1.01(0.99,1.03) 0.3   
Male gender 1.37(0.66,2.83) 0.4   
Functional status
 Partially dependent 1 -   
 Totally dependent 0.79(0.25,2.52) 0.69   
 Totally independent 0.79(0.38,1.61) 0.51   
Underlying medical conditions
 DM 0.90(0.46,1.75) 0.75   
 Chronic renal failure 1.89(0.82,4.33) 0.13   
 Immunosuppresant medication 1.66(0.56,4.94) 0.36   
Clinical presentation at admission
 Consciousness disturbance 1.77(0.88,3.56) 0.11   
 Temperature  > 38 °C 1.58(0.77,3.22) 0.21   
 Dyspnea 2.68(1.32,5.45) 0.007 2.29(0.81,6.43) 0.117
 Systolic BP < 90 mmHg 2.03(1.02,4.06) 0.045 1.14(0.4,3.2) 0.810
 SIRS 2.08(0.73,5.88) 0.17   
 Pus at infection site 0.73(0.31,1.68) 0.45   
Admission lab data
 Hemoglobulin (mg/dl) 0.90(0.78,1.04) 0.14   
 Leukocyte (103/mm3) 0.99(0.95,1.02) 0.38   
 Platelet (103/mm3) 0.995(0.99,0.999) 0.008 1(0.99,1) 0.056
 Potassium (mEq/l) 1.57(1.06,2.31) 0.023 2.2(1.2,4.02) 0.011
 Positive blood culture 2.31(1.05,5.08) 0.037 1.95(0.71,5.38) 0.197
Time to surgery <12 h 0.83(0.41,1.68) 0.598   
  1. (n = 165)
  2. OR odds ratio, CI confidence interval, SIRS systemic inflammatory response syndrome