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Table 4 Clinical characteristics of the survivors and non-survivors among necrotizing fasciitis patients

From: Necrotizing fasciitis in patients with diabetes mellitus: clinical characteristics and risk factors for mortality

Variable

Survivors (n = 116)

Non-survivors (n = 49)

P value

Age

57.8 ± 17.9

61 ± 16.4

0.297

Male gender

75(64.7)

35(71.4)

0.399

American Society of Anaesthesiologists (ASA) score

 1

13(11.2)

5(10.2)

0.268

 2

33(28. 5)

10(20.4)

 

 3

50(43.1)

19(38. 8)

 

 4

20(17.2)

15(30.6)

 

Pre-existing medical conditions

 Diabetes mellitus

60(51.7)

24(49.0)

0.747

 Hypertension

39(33.6)

20(41. 7)

0.329

 Chronic renal failure

17(14.7)

12(24.5)

0.129

 Liver cirrhosis

13(11.2)

9(18.4)

0.216

 Malignancy

10(8.6)

4(8.2)

1

 Immunosuppresant medication

9(7.8)

6(12.2)

0.382

Admission lab data

 Hemoglobin (mg/dl)

10.8 ± 2.4

10.1 ± 2.6

0.135

 Leukocyte count (103/mm3)

11.3 ± 11.3

9.7 ± 9.9

0.3777

 Platelet count (103/mm3)

193.7 ± 128.8

135.2 ± 89.0

0.0021

 C-reactive protein > 10 mg/dla

58(79. 5)

29(78.4)

0896

 Glucose > 110 mg/dlb

39(65)

19(82.61)

0.356

 Potassium (mEq/l)

4.0 ± 0.9

4.5 ± 1.2

0.034

 Positive blood culturec

33(38.82)

22(59.46)

0.035

Location of infection

 body

9(7.8)

12(24.5)

0.025

 head and neck

3(2.6)

1(2.0)

 

 upper limb

10(8.6)

7(14.3)

 

 lower limb

84(72.4)

27(55.1)

 

 multiple sites

10(8.6)

2(4.1)

 

Time to surgery <12 h

62(54.39)

25(54.35)

0.531

ICU stay (day)

9.5 ± 12.1

9.5 ± 10.4

0.977

Hospital stay (day)

51.7 ± 33.4

13.6 ± 14.4

<.0001

Limb loss

28(24.1)

7(14.3)

0.157

  1. In Tables 3 and 4, data presented as mean ± standard deviation for continuous data or number (%) for categorical data
  2. adata derived from 103 of the 165 cases
  3. bdata derived from 72 of the 165 cases
  4. cdata derived from 114 of the 165 cases