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Table 4 Clinical characteristics of the survivors and non-survivors among necrotizing fasciitis patients

From: Necrotizing fasciitis in patients with diabetes mellitus: clinical characteristics and risk factors for mortality

Variable Survivors (n = 116) Non-survivors (n = 49) P value
Age 57.8 ± 17.9 61 ± 16.4 0.297
Male gender 75(64.7) 35(71.4) 0.399
American Society of Anaesthesiologists (ASA) score
 1 13(11.2) 5(10.2) 0.268
 2 33(28. 5) 10(20.4)  
 3 50(43.1) 19(38. 8)  
 4 20(17.2) 15(30.6)  
Pre-existing medical conditions
 Diabetes mellitus 60(51.7) 24(49.0) 0.747
 Hypertension 39(33.6) 20(41. 7) 0.329
 Chronic renal failure 17(14.7) 12(24.5) 0.129
 Liver cirrhosis 13(11.2) 9(18.4) 0.216
 Malignancy 10(8.6) 4(8.2) 1
 Immunosuppresant medication 9(7.8) 6(12.2) 0.382
Admission lab data
 Hemoglobin (mg/dl) 10.8 ± 2.4 10.1 ± 2.6 0.135
 Leukocyte count (103/mm3) 11.3 ± 11.3 9.7 ± 9.9 0.3777
 Platelet count (103/mm3) 193.7 ± 128.8 135.2 ± 89.0 0.0021
 C-reactive protein > 10 mg/dla 58(79. 5) 29(78.4) 0896
 Glucose > 110 mg/dlb 39(65) 19(82.61) 0.356
 Potassium (mEq/l) 4.0 ± 0.9 4.5 ± 1.2 0.034
 Positive blood culturec 33(38.82) 22(59.46) 0.035
Location of infection
 body 9(7.8) 12(24.5) 0.025
 head and neck 3(2.6) 1(2.0)  
 upper limb 10(8.6) 7(14.3)  
 lower limb 84(72.4) 27(55.1)  
 multiple sites 10(8.6) 2(4.1)  
Time to surgery <12 h 62(54.39) 25(54.35) 0.531
ICU stay (day) 9.5 ± 12.1 9.5 ± 10.4 0.977
Hospital stay (day) 51.7 ± 33.4 13.6 ± 14.4 <.0001
Limb loss 28(24.1) 7(14.3) 0.157
  1. In Tables 3 and 4, data presented as mean ± standard deviation for continuous data or number (%) for categorical data
  2. adata derived from 103 of the 165 cases
  3. bdata derived from 72 of the 165 cases
  4. cdata derived from 114 of the 165 cases