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Table 3 Clinical characteristics of the non-diabetic and diabetic cohorts among necrotizing fasciitis patients

From: Necrotizing fasciitis in patients with diabetes mellitus: clinical characteristics and risk factors for mortality

Variable DM (n = 84) Non-DM (n = 81) P value
Age 61.5 ± 10.6 56 ± 22.2 0.045
Male gender 58(69.1) 52(64.2) 0.509
American Society of Anaesthesiologists (ASA) score
 1 4(4.8) 14(17.3) 0.079
 2 23(27.4) 20(24.7)  
 3 37(44.0) 32(39.5)  
 4 20(23.8) 15(18.5)  
Pre-existing medical conditions
 Hypertension 35(42.2) 24(29.6) 0.094
 Chronic renal failure 19(22.6) 10(12.4) 0.083
 Liver cirrhosis 12(14.3) 10(12.4) 0.714
 Malignancy 6(7.1) 8(9.9) 0.529
 Immunosuppresant medication 7(8.3) 8(9.9) 0.730
Admission lab data
 Hemoglobin (mg/dl) 10.4 ± 2.5 10.8 ± 2.5 0.321
 Leukocyte count (103/mm3) 11.1 ± 9.9 10.5 ± 11.8 0.767
 Platelet count (103/mm3) 188.8 ± 129.5 160.7 ± 109.3 0.167
 C-reactive protein > 10 mg/dla 43(75.4) 44(83.0) 0.329
 Glucose > 110 mg/dlb 41(85.4) 17(48.6) <0.001
 Potassium (mEq/l) 4.4 ± 1.1 4.0 ± 0.8 0.010
 Positive blood culturec 28(41.8) 27(49.1) 0.420
Location of infection
 body 10(11.9) 11(13.6) 0.651
 head and neck 3(3.6) 1(1.2)  
 upper limb 9(10.7) 8(9.9)  
 lower limb 54(64.3) 57(70.4)  
 multiple sites 8(9.5) 4(4.9)  
Time to surgery <12 h 43(51.2) 44(54.3) 0.687
ICU stay (day) 9.3 ± 10.8 9.8 ± 12.1 0.793
Hospital stay (day) 39.1 ± 28.6 41.1 ± 38.4 0.712
Limb loss 24(28.6) 11(13.6) 0.019
Mortality 24(28.6) 25(30.9) 0.747