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Table 1 Definitions of clinical parameters

From: Necrotizing fasciitis in patients with diabetes mellitus: clinical characteristics and risk factors for mortality

Variable Definition
Diabetes mellitus The diagnosis is based on one of four abnormalities outlined by American Diabetes Association, 2010: glycated hemoglobin (A1C) ≥6.5 %, fasting plasma glucose (FPG) ≥126 mg/dl, random plasma glucose ≥200 mg/dl with symptoms, or two-hour plasma glucose ≥200 mg/dl during an oral glucose tolerance test (OGTT)
Functional status Patient requiring no, partial or totally dependent assistance from another person for activities of daily living before surgery
Hypertension Patient with elevated blood pressure requiring medication
Chronic renal failure Patient with a rising creatinine >3 mg/dl or a decreased glomerular filtration rate of less than 60 ml/min/1.73 m2 for 3 or more months
Liver cirrhosis Diagnosis based on clinical, laboratory and echographic findings
SIRS Includes the presence of two or more of the following: temperature >38 °C or <36 °C, heart rate >90 bpm, respiratory rate >20 breaths/min or PaCO2 < 32 mm/Hg, WBC >12,000/mm3 or <4000/mm3, or >10 % immature (band) forms, anion gap acidosis
Septic shock Includes sepsis and documented organ and/or circulatory dysfunction
ASA score 1 = normal healthy patient
2 = patient with mild systemic disease
3 = patient with severe systemic disease
4 = patient with severe systemic disease that is a constant threat to life
5 = moribund patient who is not expected to survive without the operation
Limb loss Amputation of the lower or upper limb above the ankle or the wrist, respectively.
  1. SIRS systemic inflammatory response syndrome, ASA American Society of Anesthesiologists