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Table 1 Demographic and clinical baseline characteristics

From: Genotypic distribution and hepatic fibrosis among HIV/HCV co-infected individuals in Southern China: a retrospective cross-sectional study

Demographic or clinical data

Mono-infection (n = 86)

Co-infection (n = 89)

Total (n = 175)

p-value

Age (y), mean ± SD

39.9 ± 12.6

36.6 ± 6.3

38.3 ± 9.9

0.133

Male gender, n (%)

49 (57)

72 (81)

121 (69)

0.001

Marital status, n (%)

   

0.609

 Married

55 (64)

69 (78)

124 (71)

 

 Not married

13 (15)

20 (22)

33 (19)

 

 Unknown

18 (21)

0 (0)

18 (10)

 

Education status, n (%)

   

<0.001

  < HS education, n (%)

12 (14)

74 (83)

86 (49)

 

  > HS education

47 (55)

15 (17)

62 (35)

 

 Unknown

27 (31)

0 (0)

27 (15)

 

Employment status, n (%)

   

0.280

 Employed or student

47 (55)

56 (63)

103 (59)

 

 Unemployed

19 (22)

33 (37)

52 (30)

 

 Unknown

20 (23)

0 (0)

20 (11)

 

HCV risk factor, n (%)

   

<0.001

 IDU

3 (4)

72 (81)

75 (43)

 

 Blood transfusion

37 (43)

2 (2)

39 (22)

 

 Sexual

0 (0)

11 (12)

11 (6)

 

 Othera

46 (54)

4 (5)

50 (29)

 

 Unknown

25 (29)

1 (1)

26 (15)

 

HCV genotype, n (%)

   

<0.001

 1a

3 (4)

1 (1)

4 (2)

0.362

 1b

57 (66)

15 (17)

72 (41)

<0.001

 2a

5 (6)

1 (1)

6 (3)

0.113

 3a

3 (3)

16 (18)

19 (11)

0.002

 3b

6 (7)

9 (10)

15 (9)

0.459

 6a

12 (14)

47 (53)

59 (34)

<0.001

AST, median (IQR)

38 (29–65)

54 (36–92)

43 (32–73)

0.004

ALT, median (IQR)

47.5 (32–90)

49 (33–81)

49 (32–85)

0.794

Platelet count (^10),

185 ± 69

179 ± 69

182 ± 69

0.644

 mean ± SD

APRI scoreb, n (%)

   

0.012

 Class 1

43 (50)

26 (28)

68 (39)

 

 Class 2

26 (30)

40 (45)

66 (38)

 

 Class 3

17 (20)

24 (27)

41 (23)

 

FIB-4 scorec, n (%)

   

0.009

 Class 1

55 (64)

41 (46)

96 (55)

 

 Class 2

15 (17)

34 (38)

49 (28)

 

 Class 3

16 (19)

14 (16)

30 (17)

 
  1. Abbreviations: IDU intravenous drug use
  2. aOther iatrogenic is defined by reporting of HCV transmission route through other medical or dental routes besides blood transfusion
  3. bAPRI Categories: APRI Class 1 (Score < 0.5), APRI Class 2 (Score 0.51–1.5), APRI Class 3 (Score > 1.5)
  4. cFIB-4 Categories: FIB-4 Class 1 (Score < 1.45), FIB-4 Class 2 (Score 1.46–3.25), FIB-4 Class 3 (Score > 3.25)
  5. Bold p-values are significant at the 0.05 level