Skip to main content

Table 1 Demographic and clinical baseline characteristics

From: Genotypic distribution and hepatic fibrosis among HIV/HCV co-infected individuals in Southern China: a retrospective cross-sectional study

Demographic or clinical data Mono-infection (n = 86) Co-infection (n = 89) Total (n = 175) p-value
Age (y), mean ± SD 39.9 ± 12.6 36.6 ± 6.3 38.3 ± 9.9 0.133
Male gender, n (%) 49 (57) 72 (81) 121 (69) 0.001
Marital status, n (%)     0.609
 Married 55 (64) 69 (78) 124 (71)  
 Not married 13 (15) 20 (22) 33 (19)  
 Unknown 18 (21) 0 (0) 18 (10)  
Education status, n (%)     <0.001
  < HS education, n (%) 12 (14) 74 (83) 86 (49)  
  > HS education 47 (55) 15 (17) 62 (35)  
 Unknown 27 (31) 0 (0) 27 (15)  
Employment status, n (%)     0.280
 Employed or student 47 (55) 56 (63) 103 (59)  
 Unemployed 19 (22) 33 (37) 52 (30)  
 Unknown 20 (23) 0 (0) 20 (11)  
HCV risk factor, n (%)     <0.001
 IDU 3 (4) 72 (81) 75 (43)  
 Blood transfusion 37 (43) 2 (2) 39 (22)  
 Sexual 0 (0) 11 (12) 11 (6)  
 Othera 46 (54) 4 (5) 50 (29)  
 Unknown 25 (29) 1 (1) 26 (15)  
HCV genotype, n (%)     <0.001
 1a 3 (4) 1 (1) 4 (2) 0.362
 1b 57 (66) 15 (17) 72 (41) <0.001
 2a 5 (6) 1 (1) 6 (3) 0.113
 3a 3 (3) 16 (18) 19 (11) 0.002
 3b 6 (7) 9 (10) 15 (9) 0.459
 6a 12 (14) 47 (53) 59 (34) <0.001
AST, median (IQR) 38 (29–65) 54 (36–92) 43 (32–73) 0.004
ALT, median (IQR) 47.5 (32–90) 49 (33–81) 49 (32–85) 0.794
Platelet count (^10), 185 ± 69 179 ± 69 182 ± 69 0.644
 mean ± SD
APRI scoreb, n (%)     0.012
 Class 1 43 (50) 26 (28) 68 (39)  
 Class 2 26 (30) 40 (45) 66 (38)  
 Class 3 17 (20) 24 (27) 41 (23)  
FIB-4 scorec, n (%)     0.009
 Class 1 55 (64) 41 (46) 96 (55)  
 Class 2 15 (17) 34 (38) 49 (28)  
 Class 3 16 (19) 14 (16) 30 (17)  
  1. Abbreviations: IDU intravenous drug use
  2. aOther iatrogenic is defined by reporting of HCV transmission route through other medical or dental routes besides blood transfusion
  3. bAPRI Categories: APRI Class 1 (Score < 0.5), APRI Class 2 (Score 0.51–1.5), APRI Class 3 (Score > 1.5)
  4. cFIB-4 Categories: FIB-4 Class 1 (Score < 1.45), FIB-4 Class 2 (Score 1.46–3.25), FIB-4 Class 3 (Score > 3.25)
  5. Bold p-values are significant at the 0.05 level