The role of vancomycin in addition with colistin and meropenem against colistin-sensitive multidrug resistant Acinetobacter baumannii causing severe infections in a Paediatric Intensive Care Unit

Table 1 Clinical characteristics and microbiological data of patients

Patient	Age	Underlying disease	Diagnosis at admission	Type of infection	Treatment (duration, days)		Outcome^d
Patient	Age	Underlying disease	Diagnosis at admission	Type of infection	Initial	Definitive	Outcome^d
Case#1	3 mo^a	Pierre Robin Syndrome	Septic shock (A. baumannii BSI)	BSI	RIF + COL (5)	VAN + COL + MEM (12)	Late relapse (UTI) Cured
Case#2	21 ys	Spastic tetraparesis; dysphagia	Respiratory failure^b	VAP & BSI	RIF + COL (5)	VAN + COL + MEM (15)	Cured
Case#3	25 ys	Spastic tetraparesis	Respiratory failure^b	BSI	VAN + COL + MEM (16)	VAN + COL + MEM^c	Cured
Case#4	6 mo	None	ARDS	VAP	VAN + COL + MEM (19)	VAN + COL + MEM^c	Cured

COL colistin, VAN vancomycin, RIF rifampin, MEM meropenem, UTI urinary Tract Infection, BSI bloodstream infection, VAP Ventilator-Acquired Pneumonia, ARDS Acute Respiratory Distress Syndrome
(^a): Case-index; (^b): caused by the underlying disease; (^c): in cases #3-4 the initial therapy was the definitive one; (^d): at least 3-months follow-up

ISSN: 1471-2334