Longitudinal immune profiles in type 1 leprosy reactions in Bangladesh, Brazil, Ethiopia and Nepal

BMC Infectious Diseases

Table 1 Participating study sites and study groups

Site	Category^a	Mean BI^b	Sex ratio	Age range	Total^c
			(M/F)	(yr)
Bangladesh	EC	na^d	0.9	20–40	20
	BL/LL	2.20	5	18–61	31
	RR	1.68	2.5	21–63	20
Brazil	EC	na^d	1.3	24–76	23
	BL/LL	1.51	1	22–26	25
	RR	1.95	3.3	25–68	20
Ethiopia	EC	na^d	1.8	18–45	11
	BL/LL	1.25	1.7	18–52	25
	RR	0.46	2.8	18–60	15
Nepal	EC	na^d	3.6	19–28	20
	BL/LL	2.96	2	35–58	13
	RR	1.45	2.5	27–50	20

^aEC endemic control, BL/LL borderline leprosy/ lepromatous leprosy, TT/BT tuberculoid leprosy/ borderline tuberculoid leprosy, RR reversal reaction (type 1 reaction)
^bBI bacterial index (mean)
^cTotal number of recruited individuals is indicated; samples for multiple time points were not always included. For multiplex cytokine analysis or UPLC-ESI-TOF MS a selected sample size was used for analysis
^dnot applicable

ISSN: 1471-2334