Characteristic | All data n = 500 | Blood culture negative n = 461 | Blood culture positive n = 39 | OR (95 % CI) |
---|---|---|---|---|
N (%) or Median (IQR) | N (%) or Median (IQR) | N (%) or Median (IQR) | ||
Blood volume (mls) | 8.89 (6.18, 11.1) | 8.83 (6.06, 11) | 9.47 (7.5, 11.3) | 1.05 (0.97, 1.12) |
Weight (kg) | 72.6 (69.4, 76.2) | 72.6 (69.3, 76.2) | 73.1 (70.9, 75.7) | 0.99 (0.98, 1) |
Age (years) | 48 (31, 64) | 47 (31, 64) | 51 (32, 64.5) | 1.01 (0.99, 1.02) |
Temperature (C) | 37.4 (36.2, 38.4) | 37.4 (36.2, 38.4) | 37.4 (36.4, 38.5) | 1.14 (0.92, 1.45) |
Pulse (bpm) | 110 (93, 122) | 109 (92, 122) | 117 (100, 130) | 1.02 (1, 1.04) |
Respiratory rate (bpm) | 22 (18, 28) | 22 (18, 28) | 24 (20, 29.8) | 1.02 (0.98, 1.06) |
Oxygen saturations | 96 (92, 98) | 96 (92, 98) | 96 (91, 98) | 0.99 (0.94, 1.05) |
Inspired oxygen concentration (%) | 21 (21, 21) | 21 (21, 21) | 21 (21, 21) | 1.01 (0.99, 1.02) |
Chills present | 210 (43.8) | 190 (43) | 20 (52.6) | 1.57 (0.83, 3) |
Confusion present | 142 (29.5) | 130 (29.4) | 12 (30.8) | 1.09 (0.53, 2.11) |
CRB 65 score | ||||
0 | 169 (33.8) | 161 (34.9) | 8 (20.5) | 1.00 (ref) |
1 | 191 (38.2) | 173 (37.5) | 18 (46.1) | 1.69 (0.78, 3.87) |
2 | 101 (20.2) | 95 (20.6) | 6 (15.4) | 1.03 (0.34, 2.85) |
3 | 35 (7) | 29 (6.3) | 6 (15.4) | 3.21 (1.03, 9.32) |
4 | 4 (0.8) | 3 (0.6) | 1 (2.6) | 5.53 (0.26, 47.95) |
Diabetic | 111 (22.2) | 96 (20.8) | 15 (38.5) | 2.08 (1.04, 4.01) |
HIV infected | 96 (19.2) | 87 (18.9) | 9 (23.1) | 1.33 (0.6, 2.72) |
Hospital | ||||
GSH | 409 (82) | 374 (81.3) | 35 (89.7) | 1.00 (ref) |
VIC | 90 (18) | 86 (18.7) | 4 (10.3) | 0.43 (0.13, 1.1) |
Diastolic blood pressure <60 mmHg | 138 (28) | 118 (26) | 20 (51.3) | 2.48 (1.3, 4.7) |
Systolic blood pressure <90 mmHg | 38 (7.7) | 30 (6.6) | 8 (21.1) | 3.26 (1.31, 7.34) |
Sex | ||||
Female | 263 (52.6) | 244 (52.9) | 19 (48.7) | 1.00 (ref) |
Male | 237 (47.4) | 217 (47.1) | 20 (51.3) | 1.38 (0.74, 2.63) |
Current malignancy present | 35 (7) | 30 (6.5) | 5 (12.8) | 2.52 (0.9, 6.09) |
Antibiotics in previous 48 h | 84 (17.2) | 80 (17.8) | 4 (10.3) | 0.51 (0.15, 1.33) |
Source (reduced categories – used in all modelling) | ||||
Othersa | 88 (17.6) | 86 (18.7) | 2 (5.1) | 0.32 (0.05,1.17) |
Biliary | 19 (3.8) | 12 (2.6) | 7 (17.9) | 9.42 (3.25, 26.83) |
LRTI | 206 (41.2) | 195 (42.3) | 11 (28.2) | 1.00 (ref) |
Meningitis | 28 (5.6) | 24 (5.2) | 4 (10.3) | 2.36 (0.63, 7.24) |
Unknown | 103 (20.6) | 93 (20.2) | 10 (25.6) | 1.59 (0.66, 3.75) |
UTI | 56 (11.2) | 51 (11.1) | 5 (12.8) | 1.44 (0.45, 4.02) |