Application of a methicillin-resistant Staphylococcus aureus risk score for community-onset pneumonia patients and outcomes with initial treatment

Table 1 Antibiotic therapy definitions

MRSA therapy
• Vancomycin
• Linezolid
Guideline-Concordant CAP therapy
Ward patients	ICU patients
• Beta-lactam^a plus (macrolide^b or doxycycline)	• Beta-lactam^a plus (macrolide^b or doxycycline)
• Respiratory fluoroquinolone^c	• Beta-lactam^a plus respiratory fluoroquinolone^c
Pseudomonal therapy
• Antipseudomonal beta-lactam^d plus antipseudomonal fluoroquinolone^e
• Antipseudomonal beta-lactam^d plus aminoglycoside^f
Atypical therapy
• Macrolide^b
• Doxycycline
• Any fluoroquinolone

CAP Community-acquired pneumonia, ICU Intensive care unit
^aBeta-lactam includes cefotaxime, ceftriaxone, ampicillin-sulbactam, ertapenum, or aztreonam
^bMacrolide includes azithromycin, clarithromycin, or erythromycin
^cRespiratory fluoroquinolone includes moxifloxacin, levofloxacin, or gatifloxacin
^dAntipseudomonal beta-lactam includes cefepime, ceftazidime, imipenem-cilastatin, meropenem, piperacillin-tazobactam, or ticarcillin-clavulanate, aztreonam
^eAntipseudomonal fluoroquinolone includes ciprofloxacin or levofloxacin
^fAminoglycoside includes gentamicin, tobramycin, or amikacin

ISSN: 1471-2334