Table 1 Virucidal activity of 4 different PVP-I preparations against MVA
Test product | Dilution | Log10 reduction factor (95 % confidence interval, where applicable) | |||||
|---|---|---|---|---|---|---|---|
Clean conditions | Dirty conditions | ||||||
Application time | Application time | ||||||
15 s | 30 s | 60 s | 15 s | 30 s | 60 s | ||
PVP-I solution (10 g/L available iodine) | Undiluted (10 g/L) | ≥4.00 | ≥4.00 | ≥4.00 | ≥4.17 | ≥4.17 | ≥4.17 |
1:10 (1 g/L) | ≥5.67 | ≥5.67 | ≥5.67 | ≥5.50 | ≥5.50 | ≥5.50 | |
1:100 (0.1 g/L) | 4.33 (±0.63) | 5.67 (±0.60) | ≥6.33 | 2.83 (±0.54) | 3.50 (±0.65) | 3.50 (±0.54) | |
PVP-I surgical scrub (7.5 g/L available iodine) | Undiluted (7.5 g/L) | ≥4.00 | ≥4.00 | ≥4.00 | ≥4.17 | ≥4.17 | ≥4.17 |
1:10 (0.75 g/L) | ≥5.50 | ≥5.50 | ≥5.50 | ≥5.67 | ≥5.67 | ≥5.67 | |
1:100 (0.075 g/L) | 3.83 (±0.65) | 4.17 (±0.58) | 4.50 (±0.58) | 1.00 (±0.70) | 1.67 (±0.70) | 1.83 (±0.71) | |
PVP-I skin cleanser (4 g/L available iodine) | Undiluted (4 g/L) | ≥4.17 | ≥4.17 | ≥4.17 | ≥4.00 | ≥4.00 | ≥4.00 |
1:10 (0.4 g/L) | 4.50 (±0.54) | ≥4.67 | ≥4.67 | 4.33 (±0.56) | ≥4.50 | ≥4.50 | |
1:100 (0.04 g/L) | 3.33 (±0.56) | 3.67 (±0.47) | 3.67 (±0.47) | 0.33 (±0.56) | 1.00 (±0.63) | 1.00 (±0.63) | |
PVP-I/alcohol solution (3.2 g/L available iodine) | Undiluted (3.2 g/L) | ≥5.67 | ≥5.67 | ≥5.67 | ≥5.67 | ≥5.67 | ≥5.67 |
1:10 (0.32 g/L) | 5.50 (±0.54) | 6.33 (±0.56) | 6.33 (±0.56) | 3.00 (±0.63) | 4.00 (±0.47) | 4.83 (±0.33) | |
1:100 (0.032 g/L) | 1.83 (±0.54) | 2.00 (±0.60) | 2.50 (±0.54) | −0.17 (±0.68) | 0.00 (±0.60) | 0.17 (±0.54) | |