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Table 1 Characteristics of the patients according to the multi-drug resistant organisms (MDRO) carrier status

From: First multicenter study on multidrug resistant bacteria carriage in Chinese ICUs

Characteristic Total Type of MDRO carriage
  patients On admission ICU-acquired Not carrier P value*
  n (%) n (%) n (%) n (%)  
Total 686 (100.0) 247 (100.0) 104 (100.0) 335 (100.0)  
Male (yes) 405 (59.0) 149 (60.3) 63 (60.6) 193 (57.6) 0.59
Severe/critical status on admission 525 (75.5) 192 (77.7) 87 (83.7) 246 (73.4) 0.04
Previous hospitalization 190 (27.7) 121 (49.0) 46 (44.2) 125 (37.3) 0.21
Origin of patients before ICUa
- community 28 (4.1) 12 (4.9) 5 (4.8) 11 (3.3) reference
- emergency room 115 (16.8) 40 (16.2) 30 (28.9) 45 (13.4) 1.0
- other wards 494 (72.0) 173 (70.0) 61 (58.7) 260 (77.6) 0.21
- other hospitals 30 (4.4) 13 (5.2) 6 (5.8) 11 (3.3) 0.58
- others/ no data 16 (2.3) 7 (2.8) 2 (1.9) 7 (2.1) 1.0
Invasive devices before ICU 313 (45.6) 132 (53.4) 48 (46.2) 133 (39.7) 0.24
Invasive devices in ICU 640 (93.3) 233 (94.3) 102 (98.1) 305 (91.0) 0.02
- mechanical ventilation 381 (55.5) 135 (54.7) 66 (63.5) 180 (53.7) 0.08
- indwelling urinary catheter 629 (91.7) 224 (90.7) 98 (94.2) 307 (91.6) 0.39
- intravascular catheter 514 (74.9) 200 (81.0) 88 (84.6) 226 (67.5) 0.001
Antibiotic in the last 3 months 279 (40.7) 118 (47.8) 58 (55.8) 103 (30.7) <0.001
Antibiotic on ICU admission 586 (85.6) 204 (82.6) 89 (85.6) 293 (87.7) 0.57
- > 1 drug 232 (33.8) 82 (33.2) 39 (37.5) 111 (33.1) 0.41
Antibiotic in ICU
- none 37 (5.4) 17 (6.9) 5 (4.8) 15 (4.5) reference
- 1 drug 314 (45.8) 107 (43.3) 33 (31.7) 174 (51.9) 0.34
- 2 drugs 210 (30.6) 69 (27.9) 28 (26.9) 113 (33.7) 0.56
- > 2 drugs (3–7) 125 (18.2) 54 (21.9) 38 (36.6) 33 (9.9) 0.04
- penicillins 8 (1.2) 3 (1.2) 0 5 (1.5) 0.60
- penicillins + inhibitors 192 (28.0) 72 (29.2) 46 (44.2) 74 (22.1) <0.001
- cephalosporins 1st & 2nd G 155 (22.6) 51 (20.7) 13 (12.5) 91 (27.2) 0.002
- cephalosporins 3rd G /aztreonam 223 (32.5) 79 (32.0) 40 (38.5) 104 (31.0) 0.16
- carbapenems 140 (20.4) 61 (24.7) 30 (29.9) 49 (14.6) 0.001
- aminoglycosides 13 (1.9) 4 (1.6) 4 (3.9) 5 (1.5) 0.23
- fluoroquinolones 111 (16.2) 45 (18.2) 15 (14.4) 51 (15.2) 0.84
- glycopeptides 116 (16.9) 45 (18.2) 33 (31.7) 38 (11.3) <0.001
- others 194 (28.3) 69 (27.9) 32 (30.8) 93 (27.8) 0.55
Type of discharge at 28 ICU daysb
- discharged from hospital 83 (12.1) 35 (14.2) 16 (15.4) 32 (9.6) reference
- remain in ICU 36 (5.2) 16 (6.5) 16 (15.4) 4 (1.2) 0.001
- other ward 516 (75.2) 173 (70.0) 58 (55.8) 285 (85.3) 0.01
- death 45 (6.6) 22 (8.9) 10 (9.6) 13 (3.9) 0.44
  Median (range) Median (range) Median (range) Median (range)  
Age (year) 66 (9–101) 65 (9–101) 66 (21–95) 67 (15–94) 0.99
Length of stay (days)
- in hospital before ICU admission 6 (0 – >60) 7 (0 – >60) 4 (0 – >60) 7 (0 – >60) 0.05
- in ICU 4 (4 – >28) 4 (1 – >28) 10 (2 – >28) 4 (1 – >28) <0.001
- before MDR acquisition 7 (3 – >28) 0 7 (3 – >28) -  
Total antibiotic-days in ICU   3 (0 –27) 5 (0–21) 3 (0–25) <0.001
  1. *Comparing ICU-acquired MDRO patients to non carriers; aData are missing for 3 patients; bData are missing for 6 patients