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Table 1 Socio-demographic and clinical characteristics, and factors associated with treatment discontinuation in a cohort of 236 prisoners

From: Personality disorders do not affect treatment outcomes for chronic HCV infection in Spanish prisoners: the Perseo study

    Bivariate analysis Multivariate analysis
Variable Overall n = 236 Treatment discontinuation n = 76 (32.2 %) OR p-value p-value AOR (95 % CI)
Age group (years)       
 20–29 15 7 (46.7) 1    
 30–39 94 31 (33.0) 0.56 0.31   
 40–49 102 27 (26.5) 0.41 0.12   
 ≥50 25 11 (44.0) 0.90 0.87   
Sex       
 Male 219 69 (31.5) 1    
 Female 17 7 (41.2) 1.52 0.41   
HIV infection       
 Yes 62 25 (40.3) 1.63 0.11   
 No 174 51 (29.3) 1    
Genotype       
 1 or 4 141 56 (39.7) 1   0.004 3.55 (1.76–7.18)
 2 or 3 95 20 (21.1) 0.40 0.003   1
Genotype and HIV infection       
 No HIV and G1 or G4 97 39 (40.2) 0.99 0.99   
 No HIV and G2 or G3 77 12 (15.6) 0.27 0.001   
 HIV infection 62 25 (40.3) 1 1   
History of alcohol abuse       
 Yes 54 16 (29.6) 0.86 0.64   
 No 182 60 (33.0) 1    
History of IDU       
 Yes 187 61 (32.6) 1.10 0.79   
 No 49 15 (30.6) 1    
BVL       
 Low 88 28 (31.8) 1    
 High 148 48 (32.4) 1.03 0.92   
Personality disorder       
 Yes 129 38 (29.5) 0.44 0.01   1
 No 49 24 (49.0) 1   0.01 2.51 (1.23–5.11)
 Not available or missing 58 14 (24.1) ---    
Cluster A-PD:       
 Yes 64 20 (31.2) 0.78 0.45   
 No 114 42 (36.8) 1    
 Not available or missing 58 14 (24.1) ---    
Cluster B-PD       
 Yes 101 29 (28.7) 0.53 0.05   
 No 77 33 (42.9) 1    
 Not available o Missing 58 14 (24.1) ---    
Cluster C-PD       
 Yes 55 18 (32.7) 0.87 0.69   
 No 123 44 (35.8) 1    
 Not available or missing 58 14 (24.1) ---    
Antisocial PD       
 Yes 83 22 (26.5) 0.49 0.03   
 No 95 40 (42.1) 1    
 Not available or missing 58 14 (24.1) ---    
  1. Cluster A-PD: Paranoid, Schizoid and Schizotypal PDs; Cluster B-PD: Histrionic, Narcissistic, Borderline and Antisocial PDs; Cluster C-PD: Avoidant, Dependent and Obsessive-Compulsive PDs
  2. OR odds ratio, CI confidence interval, IDU injecting drug user, BVL baseline viral load, PD personality disorder, AOR adjusted odds ratio