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Table 1 Characteristics of 81 patients with acute bacterial meningitis and CT imaging within 24 h of diagnosis according to 30-day survival

From: Brain ventricular dimensions and relationship to outcome in adult patients with bacterial meningitis

 

All

Survivors

Non-survivors

P value

N = 81

N = 55 (68 %)

N = 26 (32 %)

Age, years

64 (52–74)

62 (51–68)

73 (54–84)

0.006

Sex

   

0.059

Male, %

44 (54 %)

34 (62 %)

10 (38 %)

 

Female, %

37 (46 %)

21 (38 %)

16 (62 %)

 

Etiology

   

0.23

Streptococcus pneumoniae

43 (53 %)

28 (51 %)

15 (58 %)

 

Streptococcus sp.

6 (7 %)

2 (4 %)

4 (15 %)

 

Staphylococcus aureus

4 (5 %)

3 (5 %)

1 (4 %)

 

Listeria monocytogenes

2 (3 %)

1 (2 %)

1 (4 %)

 

Unknown

21 (26 %)

16 (29 %)

5 (19 %)

 

Other

5 (6 %)

5 (9 %)

0 (0 %)

 

Adjuvant steroid, %

   

0.08

No

28 (35 %)

15 (27 %)

13 (50 %)

 

Yes

52 (65 %)

39 (71 %)

13 (50 %)

 

Comorbidity

   

0.39

None

51 (63 %)

32 (58 %)

19 (73 %)

 

Alcoholism

13 (16 %)

8 (15 %)

5 (19 %)

 

Malignancy

5 (6 %)

5 (9 %)

0 (0 %)

 

Diabetes mellitus

5 (6 %)

4 (7 %)

1 (4 %)

 

Asplenia

4 (5 %)

4 (7 %)

0 (0 %)

 

Other immunosupp

1 (1 %)

1 (2 %)

0 (0 %)

 

Other

2 (3 %)

1 (2 %)

1 (4 %)

 

Change in mental status, %

61 (82 %)

39 (71 %)

22 (85 %)

0.20

Focal neurologic deficit, %

17 (24 %)

15 (27 %)

2 (8 %)

0.07

Seizures, %

5 (7 %)

4 (7 %)

1 (4 %)

1.0

Temperature, ° C, n = 64

38.9 (37.9-39.5)

38.8 (37.7-39.4)

39.0 (38.0-39.5)

0.49

MAP, mmHg, n = 64

102 (88–110)

103 (92–112)

94 (77–109)

0.18

White Blood Cell Count, 109/L, n = 64

17.1 (12.1-22.6)

17.9 (12.5-24.0)

15.7 (11.9-22.9)

0.29

Plasma C-reactive Protein, mg/L

227 (144–337)

238 (151–334)

192 (87–369)

0.51

CSF-leukocytes

2182 (523–6188)

1932 (488–5150)

2826 (561–7930)

0.43

CSF-protein, n = 55

4.9 (2.5-7.8)

3.3 (2.1-6.2)

6.3 (5.1-11.2)

0.001

CSF-glucose, n = 59

1.5 (0.1-2.9)

1.4 (0.1-3.3)

1.5 (0.1-2.4)

0.40

VBR

0.10 (0.07-0.14)

0.09 (0.07-0.13)

0.13 (0.10-0.15)

0.005

VBR

   

0.005

<0.08

27 (33 %)

24 (44 %)

3 (11 %)

 

0.08-1.2

25 (31 %)

17 (31 %)

8 (31 %)

 

>0.12

29 (36 %)

14 (25 %)

15 (58 %)

 
  1. MAP mean arterial pressure, CSF cerebrospinal fluid, VBR ventricle to brain ratio