Skip to main content

Table 1 Characteristics of 81 patients with acute bacterial meningitis and CT imaging within 24 h of diagnosis according to 30-day survival

From: Brain ventricular dimensions and relationship to outcome in adult patients with bacterial meningitis

  All Survivors Non-survivors P value
N = 81 N = 55 (68 %) N = 26 (32 %)
Age, years 64 (52–74) 62 (51–68) 73 (54–84) 0.006
Sex     0.059
Male, % 44 (54 %) 34 (62 %) 10 (38 %)  
Female, % 37 (46 %) 21 (38 %) 16 (62 %)  
Etiology     0.23
Streptococcus pneumoniae 43 (53 %) 28 (51 %) 15 (58 %)  
Streptococcus sp. 6 (7 %) 2 (4 %) 4 (15 %)  
Staphylococcus aureus 4 (5 %) 3 (5 %) 1 (4 %)  
Listeria monocytogenes 2 (3 %) 1 (2 %) 1 (4 %)  
Unknown 21 (26 %) 16 (29 %) 5 (19 %)  
Other 5 (6 %) 5 (9 %) 0 (0 %)  
Adjuvant steroid, %     0.08
No 28 (35 %) 15 (27 %) 13 (50 %)  
Yes 52 (65 %) 39 (71 %) 13 (50 %)  
Comorbidity     0.39
None 51 (63 %) 32 (58 %) 19 (73 %)  
Alcoholism 13 (16 %) 8 (15 %) 5 (19 %)  
Malignancy 5 (6 %) 5 (9 %) 0 (0 %)  
Diabetes mellitus 5 (6 %) 4 (7 %) 1 (4 %)  
Asplenia 4 (5 %) 4 (7 %) 0 (0 %)  
Other immunosupp 1 (1 %) 1 (2 %) 0 (0 %)  
Other 2 (3 %) 1 (2 %) 1 (4 %)  
Change in mental status, % 61 (82 %) 39 (71 %) 22 (85 %) 0.20
Focal neurologic deficit, % 17 (24 %) 15 (27 %) 2 (8 %) 0.07
Seizures, % 5 (7 %) 4 (7 %) 1 (4 %) 1.0
Temperature, ° C, n = 64 38.9 (37.9-39.5) 38.8 (37.7-39.4) 39.0 (38.0-39.5) 0.49
MAP, mmHg, n = 64 102 (88–110) 103 (92–112) 94 (77–109) 0.18
White Blood Cell Count, 109/L, n = 64 17.1 (12.1-22.6) 17.9 (12.5-24.0) 15.7 (11.9-22.9) 0.29
Plasma C-reactive Protein, mg/L 227 (144–337) 238 (151–334) 192 (87–369) 0.51
CSF-leukocytes 2182 (523–6188) 1932 (488–5150) 2826 (561–7930) 0.43
CSF-protein, n = 55 4.9 (2.5-7.8) 3.3 (2.1-6.2) 6.3 (5.1-11.2) 0.001
CSF-glucose, n = 59 1.5 (0.1-2.9) 1.4 (0.1-3.3) 1.5 (0.1-2.4) 0.40
VBR 0.10 (0.07-0.14) 0.09 (0.07-0.13) 0.13 (0.10-0.15) 0.005
VBR     0.005
<0.08 27 (33 %) 24 (44 %) 3 (11 %)  
0.08-1.2 25 (31 %) 17 (31 %) 8 (31 %)  
>0.12 29 (36 %) 14 (25 %) 15 (58 %)  
  1. MAP mean arterial pressure, CSF cerebrospinal fluid, VBR ventricle to brain ratio