Low CD1c + myeloid dendritic cell counts correlated with a high risk of rapid disease progression during early HIV-1 infection

Table 2 Association between primary endpoint (CD4+ T cell count <350 cells/ml or commencement of long-term ART) and baseline characteristics

	Univariable unadjusted		Multivariable adjusted^a
Covariate	HR (95 % CI)	P^a	HR (95 % CI)	P^b
CD1c + mDC count (<10 versus ≥10 cells/μL)	6.52 (2.11–20.14)	0.001	4.76 (1.40–16.18)	0.012
CD4+ T cell count (<350 versus ≥350 cells/μL)	0.34 (0.14–0.82)	0.016	0.39 (0.11–1.37)	0.140
Viral load (<5 versus ≥5 log10 copies/mL)	1.50 (0.67–3.36)	0.320	0.55 (0.14–2.10)	0.383

CI confidence interval, HR hazard ratio. P-value from Wald test
P^a-value is from univariable cox analyses. P^b-value is from multivariable cox analyses
^aResults adjusted for CD1c + mDC counts, CD4+ T cell counts, and HIV viral loads

ISSN: 1471-2334