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Table 1 Clinical and epidemiological characteristics of seronegative individuals, EHI patients, RPs, and TPs

From: Low CD1c + myeloid dendritic cell counts correlated with a high risk of rapid disease progression during early HIV-1 infection

  NCs N = 11 EHI N = 29 RPs N = 18 TPs N = 11 P (Pa/ Pb)
Age, years 31 (28–35) 28 (22–39) 37 (23–42) 25 (22–35) NS/NS
Han ethnicity, no., (%) 11 (100 %) 29 (100 %) 18 (100 %) 11 (100 %) NS/NS
Male gender, no., (%) 11 (100 %) 29 (100 %) 18 (100 %) 11 (100 %) NS/NS
Follow-up days, days NA 1149 (862–1297) 1091 (821–1311) 1171 (990–1284) NA/NS
At baseline      
Estimated time at baseline, days NA 55 (36–100) 69 (35–102) 53 (37–81) NA/NS
Baseline CD4 + T cell counts, cells/μL 728 (568–876) 490 (312–568) 337 (265–520) 586 (499–685) 0.015/0.000
Baseline HIV-1 RNA load, log10 copies/mL NA 4.70 (3.78–5.50) 5.02 (4.24–5.78) 4.03 (3.06–5.15) NA/NS
At 12-month follow-up visit      
CD4 + T cell counts, cells/μL NA 329 (271–539) 298 (239–328) 599 (525–732) NA/0.000
HIV-1 RNA load, log10 copies/mL NA 4.50 (3.64–4.85) 4.55 (3.19–4.85) 4.45 (3.73–4.91) NA/0.902
At primary endpoint      
Estimated time at primary endpoint, days NA 340 (104–1149) 123 (79–272) 1171 (990–1284) NA/0.000
CD4 + T cell counts, cells/μL NA 321 (281–467) 311 (274–342) 422 (309–541) NA/0.027
HIV-1 RNA load, log10 copies/mL NA 4.59 (3.89–5.27) 4.59 (3.79–4.71) 4.49 (3.88–5.37) NA/0.152
  1. Data are values (% of nonmissing values) for categorical variables and medians (interquartile range) for continuous variables
  2. NCs normal controls, EHI subjects with early HIV-1 infection, RPs rapid progressors, TPs typical progressors, NA not applicable, NS not significant
  3. P-value from independent t test for normally distributed continuous variables or Mann–Whitney U test for non-normally distributed continuous variables. Pa comparisons between NCs and EHI, Pb comparisons between RPs and TPs