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Table 1 Clinical and epidemiological characteristics of seronegative individuals, EHI patients, RPs, and TPs

From: Low CD1c + myeloid dendritic cell counts correlated with a high risk of rapid disease progression during early HIV-1 infection

 

NCs N = 11

EHI N = 29

RPs N = 18

TPs N = 11

P (Pa/ Pb)

Age, years

31 (28–35)

28 (22–39)

37 (23–42)

25 (22–35)

NS/NS

Han ethnicity, no., (%)

11 (100 %)

29 (100 %)

18 (100 %)

11 (100 %)

NS/NS

Male gender, no., (%)

11 (100 %)

29 (100 %)

18 (100 %)

11 (100 %)

NS/NS

Follow-up days, days

NA

1149 (862–1297)

1091 (821–1311)

1171 (990–1284)

NA/NS

At baseline

     

Estimated time at baseline, days

NA

55 (36–100)

69 (35–102)

53 (37–81)

NA/NS

Baseline CD4 + T cell counts, cells/μL

728 (568–876)

490 (312–568)

337 (265–520)

586 (499–685)

0.015/0.000

Baseline HIV-1 RNA load, log10 copies/mL

NA

4.70 (3.78–5.50)

5.02 (4.24–5.78)

4.03 (3.06–5.15)

NA/NS

At 12-month follow-up visit

     

CD4 + T cell counts, cells/μL

NA

329 (271–539)

298 (239–328)

599 (525–732)

NA/0.000

HIV-1 RNA load, log10 copies/mL

NA

4.50 (3.64–4.85)

4.55 (3.19–4.85)

4.45 (3.73–4.91)

NA/0.902

At primary endpoint

     

Estimated time at primary endpoint, days

NA

340 (104–1149)

123 (79–272)

1171 (990–1284)

NA/0.000

CD4 + T cell counts, cells/μL

NA

321 (281–467)

311 (274–342)

422 (309–541)

NA/0.027

HIV-1 RNA load, log10 copies/mL

NA

4.59 (3.89–5.27)

4.59 (3.79–4.71)

4.49 (3.88–5.37)

NA/0.152

  1. Data are values (% of nonmissing values) for categorical variables and medians (interquartile range) for continuous variables
  2. NCs normal controls, EHI subjects with early HIV-1 infection, RPs rapid progressors, TPs typical progressors, NA not applicable, NS not significant
  3. P-value from independent t test for normally distributed continuous variables or Mann–Whitney U test for non-normally distributed continuous variables. Pa comparisons between NCs and EHI, Pb comparisons between RPs and TPs