Table 1 Matched case–control study

Baseline CD4% (mean)

19

19

NS^a

Days from baseline CD4% to estimated CD4 (mean)

393

393

NS^a

Mean age (years)

45

47

NS^a

Proportion >50 years

34 %

38 %

0.85 (0.46–1.55), NS^b

Sex (male)

90 %

90 %

1 (0.35–2.84), NS^b

History of AIDS defining illness or trough CD4 < 200

62 %

66 %

0.83 (0.44–1.57), NS^b

First line ART

84 %

88 %

0.71 (0.28–1.73), NS^b

Days ART (mean)

795

1004

NS^a

<180 days

38 %

21 %

2.30 (1.09–4.87), 0.032^b

<360 days

50 %

32 %

2.12 (1.06–4.26), 0.035^b

<720 days

62 %

45 %

1.99 (1.00–3.99), 0.058^b

ART switch (not due to virologic failure)

18 %

8 %

2.52 (0.91–7.01), 0.1 ^b

Illness

16 %

0 %

0.0001 ^b