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Table 2 Pathogens causing neonatal bloodstream infections in the three CRP groups

From: Characteristics of neonates with culture-proven bloodstream infection who have low levels of C-reactive protein (10 mg/L)

Pathogens

CRP 0–10 mg/L (n = 247)

CRP 11–100 mg/L (n = 563)

CRP > 100 mg/L (n = 176)

P value

Gram-positive organisms

184 (74.5)

322 (57.2)

63 (35.8)

<0.001

 Coagulase-negative staphylococci (CoNS)

138 (55.9)

227 (40.3)

24 (13.6)

<0.001

Staphylococcus aureus

34 (13.8)

62 (11.0)

23 (13.1)

0.715

Enterococcus spp.

8 (3.2)

18 (3.2)

1 (0.6)

0.130

Group-B streptococcus

3 (1.2)

13 (2.3)

15 (8.5)

<0.001

 Othersa

1 (0.4)

2 (0.4)

0 (0)

-

Gram-negative organisms

47 (19.0)

174 (30.9)

91 (51.7)

<0.001

E coli

12 (4.9)

41 (7.3)

23 (13.1)

0.003

Klebsiella spp.

18 (7.3)

66 (11.7)

32 (18.2)

0.001

Enterobacter spp.

4 (1.6)

26 (4.6)

11 (6.3)

0.015

Acinetobacter baumannii

6 (2.4)

23 (4.1)

12 (6.8)

0.028

Pseudomonas spp.

3 (1.2)

6 (1.1)

6 (3.4)

0.103

Serratia marscences

3 (1.2)

7 (1.2)

1 (0.6)

0.574

 Othersb

2 (0.8)

5 (0.9)

6 (3.4)

0.113

Fungemia

7 (2.8)

38 (6.7)

11 (6.3)

0.090

Polymicrobial bloodstream infection

9 (3.6)

29 (5.2)

11 (6.3)

0.214

  1. aIncluding Streptococcus pneumonia (1), and non-enterococcal group D streptococcus (2)
  2. bIncluding Citrobacter freundii (3), Stenotrophomonas maltophilia (3), Hafnia alvei (2), Neisseria Meningitidis (2), Chryseobacterium meningoseptium (1) Flavobacterium (1) and Morganella morganii (1)