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Table 2 Pathogens causing neonatal bloodstream infections in the three CRP groups

From: Characteristics of neonates with culture-proven bloodstream infection who have low levels of C-reactive protein (10 mg/L)

Pathogens CRP 0–10 mg/L (n = 247) CRP 11–100 mg/L (n = 563) CRP > 100 mg/L (n = 176) P value
Gram-positive organisms 184 (74.5) 322 (57.2) 63 (35.8) <0.001
 Coagulase-negative staphylococci (CoNS) 138 (55.9) 227 (40.3) 24 (13.6) <0.001
Staphylococcus aureus 34 (13.8) 62 (11.0) 23 (13.1) 0.715
Enterococcus spp. 8 (3.2) 18 (3.2) 1 (0.6) 0.130
Group-B streptococcus 3 (1.2) 13 (2.3) 15 (8.5) <0.001
 Othersa 1 (0.4) 2 (0.4) 0 (0) -
Gram-negative organisms 47 (19.0) 174 (30.9) 91 (51.7) <0.001
E coli 12 (4.9) 41 (7.3) 23 (13.1) 0.003
Klebsiella spp. 18 (7.3) 66 (11.7) 32 (18.2) 0.001
Enterobacter spp. 4 (1.6) 26 (4.6) 11 (6.3) 0.015
Acinetobacter baumannii 6 (2.4) 23 (4.1) 12 (6.8) 0.028
Pseudomonas spp. 3 (1.2) 6 (1.1) 6 (3.4) 0.103
Serratia marscences 3 (1.2) 7 (1.2) 1 (0.6) 0.574
 Othersb 2 (0.8) 5 (0.9) 6 (3.4) 0.113
Fungemia 7 (2.8) 38 (6.7) 11 (6.3) 0.090
Polymicrobial bloodstream infection 9 (3.6) 29 (5.2) 11 (6.3) 0.214
  1. aIncluding Streptococcus pneumonia (1), and non-enterococcal group D streptococcus (2)
  2. bIncluding Citrobacter freundii (3), Stenotrophomonas maltophilia (3), Hafnia alvei (2), Neisseria Meningitidis (2), Chryseobacterium meningoseptium (1) Flavobacterium (1) and Morganella morganii (1)