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Table 3 One-way sensitivity analysis on the vaccination coverage below which a full boys vaccination leads to more cervical cancer cases prevented than a catch-up vaccination

From: Vaccination of boys or catch-up of girls above 11 years of age with the HPV-16/18 AS04-adjuvanted vaccine: where is the greatest benefit for cervical cancer prevention in Italy?

  Vaccination coverage
Parameter varied in the sensitivity analysis 15-year-old girls catch-up 25-year-old women catch-up
% coverage (N girls) % coverage (N girls)
Base case (VE 93 %, lifetime duration of protection) 31 % (87,110) 43 % (120,830)
VE = 79 % 31 % (87,110) 43 % (120,830)
VE = 99 % 31 % (87,110) 43 % (120,830)
Vaccine duration of protection = 10 years 27 % (75,870) 30 % (84,300)
Vaccine duration of protection = 20 years 29 % (81,490) 34 % (95,540)
Vaccine duration of protection = 30 years 30 % (84,300) 39 % (109,590)
  1. VE Vaccine efficacy