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Table 3 One-way sensitivity analysis on the vaccination coverage below which a full boys vaccination leads to more cervical cancer cases prevented than a catch-up vaccination

From: Vaccination of boys or catch-up of girls above 11 years of age with the HPV-16/18 AS04-adjuvanted vaccine: where is the greatest benefit for cervical cancer prevention in Italy?

 

Vaccination coverage

Parameter varied in the sensitivity analysis

15-year-old girls catch-up

25-year-old women catch-up

% coverage (N girls)

% coverage (N girls)

Base case (VE 93 %, lifetime duration of protection)

31 % (87,110)

43 % (120,830)

VE = 79 %

31 % (87,110)

43 % (120,830)

VE = 99 %

31 % (87,110)

43 % (120,830)

Vaccine duration of protection = 10 years

27 % (75,870)

30 % (84,300)

Vaccine duration of protection = 20 years

29 % (81,490)

34 % (95,540)

Vaccine duration of protection = 30 years

30 % (84,300)

39 % (109,590)

  1. VE Vaccine efficacy