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Table 4 Distribution of msp1 block 2 alleles among study localities

From: Plasmodium falciparum merozoite surface protein 1 block 2 gene polymorphism in field isolates along the slope of mount Cameroon: a cross – sectional study

Msp1 block 2 allele type Clinical phenotype Number of positives (%) P value
All subjects Rural Semi-rural Semi-urban
K1 AP 55 (90.2) 16 (84.2) 36 (94.7) 3 (75.0) 0.260
MAD20 32 (52.5) 13 (68.4) 18 (47.4) 1 (25.0) 0.170
RO33 26 (42.6) 14 (73.7) 10 (26.3) 2 (50.0) 0.003
MR 21 (34.4) 11 (57.1) 9 (23.7) 1 (25.0) 0.034
Monoclonality 24 (39.3) 3 (15.8) 18 (47.8) 3 (75.0) 0.023
Polyclonalitya 37 (60.7) 16 (84.2) 20 (52.6) 1 (25.0) 0.023
K1 + MAD20 14 (23.0) 3 (15.8) 11 (28.9) 0 (0.0) 0.284
K1 + RO33 6 (9.8) 3 (15.8) 3 (7.9) 0 (0.0) 0.507
MAD20 + RO33 2 (3.3) 2 (10.5) 0 (0.0) 0 (0.0) 0.102
K1 + MAD20 + RO33 15 (24.6) 8 (42.1) 6 (15.8) 1 (25.0) 0.094
K1 UM 58 (71.6) 10 (71.4) 30 (71.4) 18 (72.0) 0.999
MAD20 45 (55.6) 9 (64.3) 24 (57.1) 12 (48.0) 0.591
RO33 38 (46.9) 8 (57.1) 18 (42.9) 12 (48.0) 0.645
MR 38 (46.9) 6 (42.9) 19 (45.2) 13 (52.0) 0.819
Monoclonality 34 (42.0) 3 (21.4) 21 (50.0) 10 (40.0) 0.167
Polyclonalitya 47 (58.0) 11 (78.6) 21 (50.0) 15 (60.0) 0.167
K1 + MAD20 17 (21.0) 4 (28.6) 7 (16.7) 6 (24.0) 0.578
K1 + RO33 9 (11.1) 2 (14.3) 2 (4.8) 5 (20.0) 0.145
MAD20 + RO33 8 (9.9) 3 (21.4) 3 (7.1) 2 (8.0) 0.279
K1 + MAD20 + RO33 13 (16.0) 2 (14.3) 9 (21.4) 2 (8.0) 0.344
  1. Boldface values indicate significant p values
  2. AP Asymptomatic parasitaemia, UM Uncomplicated Malaria
  3. aEstimated based on the three major allele families only