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Table 3 Individual dimension aspects related to dengue mortality according to content analysis

From: Why are people with dengue dying? A scoping review of determinants for dengue mortality

Individual dimension Consideration as determinant for dengue mortality References
SDH Concepta Observations
Age Yes • Age was more often described as a determinant than not. [2743]
• In children the most affected group were those <15 years old with an emphasis on the group of <5 years old.
• A higher frequency of dengue mortality was reported in adults (mostly in the Americas region)
• Determinant related with immunological status, type of infection and comorbidities.
Comorbidities/ Pre-existing conditions NC • Although these conditions might worsen the dengue status, there were not described as directly related to fatal outcomes. [29, 30, 4356]
• Overlaps of diseases make differential diagnosis difficult and could be considered as independent causes of death.
• The most cited were diabetes, bacterial infections and pregnancy.
Infection type/Immunological status Yes • Secondary infections, severe forms and unusual presentations were described as determinants. [29, 34, 46, 55, 5764]
Sex/Gender NC • More dengue cases were described in women, even though the majority of dengue deaths were reported in men. [27, 29, 30, 35, 37, 39, 4143, 45, 47, 52, 55, 58, 59, 6383]
• Statistically significant differences were described between sexes in dengue in severity but not in mortality.
• Gender differences in frequency were related to care-seeking behavior patterns.
Ethnicity Yes • A protective role was described for African ancestry/‘Blacks’ and a risk factor for Caucasian/ ‘Whites’. [27, 29, 30, 35, 37, 39, 52, 54, 60, 80, 8491]
• Described also as determinant related to socioeconomic status and cultural behaviors.
Occupation No • Some occupations were listed (mostly in the single case reports) but none was directly linked to fatal outcome. [32, 42, 58]
Income No • There were no individual reports on the fatal cases’ income. [92]
• Although it is related to socioeconomic status, income was not reported as a determinant for dengue mortality.
Education Yes • Level of education was described in some cases. [32, 35, 88]
• In the content analysis, it was observed that education was described as a determinant for dengue mortality related to knowledge of patients and health staff.
  1. aConcept according to what was described in the literature. YES Considered to be a determinant, NO Not considered to be a determinant, NC Non-conclusive information