All patients (n = 305) | Non-SSI subgroup (n = 143; 46.9 %) | SSI subgroup (n = 162; 53.1 %) | P | |
---|---|---|---|---|
Age (years) | 64.4 ± 14.3 | 63.5 ± 14.4 | 65.3 ± 13.8 | 0.27 |
Sex (male/ female) | 200 (65.6 %)/105 (34.4 %) | 86 (60.1 %)/57 (39.9 %) | 114 (70.4 %)/48 (29.6 %) | 0.07 |
APACHE II | 19.7 ± 7.8 | 20.5 ± 8.7 | 18.95 ± 6.6 | 0.07 |
SAPS II | 36.5 ± 17.1 | 37.9 ± 19.3 | 35.1 ± 13.9 | 0.13 |
Immunosuppression | 36 (11.8 %) | 18 (12.6 %) | 18 (11.1 %) | 0.72 |
Neutropenia on admission | 14 (4.6 %) | 7 (4.9 %) | 7 (4.3 %) | 1.00 |
HIV | 37 (12.1 %) | 19 (13.3 %) | 18 (11.1 %) | 0.60 |
Type of infection | ||||
Secondary peritonitis | 140 (45.9 %) | 71 (49.6 %) | 69 (42.6 %) | 0.09 |
Tertiary peritonitis | 165 (54.1 %) | 72 (50.4 %) | 93 (57.4 %) | 0.023 |
Inflammatory response on admission | ||||
Sepsis | 27 (8.8 %) | 11 (7.7 %) | 16 (9.8 %) | 0.85 |
Severe sepsis | 32 (10.5 %) | 15 (10.5 %) | 17 (10.5 %) | 1.00 |
Septic shock | 204 (67 %) | 89 (62.2 %) | 115 (71.1 %) | 0.006 |
Multi-organ failure | 42 (13.7 %) | 28 (19.5 %) | 14 (8.6 %) | 0.003 |
Surgery data | ||||
Urgent surgery | 276 (90.5 %) | 125 (87.4 %) | 151 (93.2 %) | 0.11 |
Percutaneous surgery | 41 (13.5 %) | 17 (11.8 %) | 24 (14.8 %) | 0.10 |
Laparoscopic surgery | 10 (3.3 %) | 4 (2.8 %) | 6 (3.7 %) | 0.28 |
Laparotomy surgery | 231 (75.7 %) | 112 (78.5 %) | 119 (73.5 %) | 0.12 |
Combined surgery | 23 (7.5 %) | 10 (6.9 %) | 13 (8 %) | 0.14 |
Number of drainages on ICU admission | 2 ± 1.7 | 1.2 ± 1.7 | 2.3 ± 1.8 | 0.01 |
Outcomes | ||||
ARDS | 121 (39.6 %) | 55 (38.4 %) | 66 (40.7 %) | 0.85 |
On mechanical ventilation | 279 (91.5 %) | 130 (90.9 %) | 149 (92 %) | 0.83 |
Arterial lactate on admission (mmol · dL−1) | 4.3 ± 3.3 | 4.1 ± 3.9 | 5.3 ± 2.5 | 0.57 |
RRT | 77 (25.2 %) | 40 (28 %) | 37 (22.8 %) | 0.35 |
Total parenteral Nutrition needs (any time) | 251 (82.3 %) | 113 (79 %) | 138 (85.2 %) | 0.17 |
ICU stay (days) | 19.8 ± 24.8 | 12.9 ± 14.2 | 22.3 ± 32.9 | 0.002 |
Hospital stay (days) | 21.7 ± 30 | 17.6 ± 35.3 | 25.4 ± 26.5 | 0.031 |
In-hospital mortality | 115 (38 %) | 64 (45.1 %) | 110 (31.7 %) | 0.018 |