Table 2 Determinants of baseline Vitamin D status (n = 260)

Phenotypic characteristics

Sex

Male

120

49 (41 %)

Ref

Ref

Female

140

91 (65 %)

2.67 (1.62 to 2.45)

<0.001

2.60(1.50 to 4.52)

0.001

Season of recruitment

Summer

137

66 (48 %)

Ref

Ref

Winter

123

74 (60 %)

1.62 (0.99 to 2.65)

0.053

1.75 (1.00 to 3.04)

0.047

Socioeconomic status^b

Lower

177

96 (54 %)

Ref

Higher

83

44 (53 %)

0.95 (0.56 to 1.60)

0.85

-

-

Extent of disease

Unilateral

144

67 (46 %)

Ref

Ref

Bilateral

116

73 (63 %)

1.95 (1.18 to 3.21)

0.009

1.89 (1.49 to 4.52)

0.025

Sputum smear

1–99 AFB per 100 HPF

106

53 (50 %)

Ref

≥100 AFB per 100 HPF

154

87 (56 %)

0.74 (0.45 to 1.22)

0.24

-

-

Age

<30 years

124

67 (54 %)

Ref

≥30 years

136

73 (54 %)

0.98 (0.60 to 1.60)

0.95

-

-

Genotypic characteristics

rs731236, VDR

AA

83

38 (46 %)

Ref

0.14

AG

115

67 (58 %)

1.65 (0.93 to 2.92)

-

-

GG

27

17 (63 %)

2.01 (0.82 to 4.91)

-

-

rs1544410,VDR

CC

53

23 (43 %)

Ref

0.098

CT

128

74 (58 %)

1.78 (0.94 to 3.41)

1.66 (0.84 to 3.28)

0.14

TT

54

34 (63 %)

2.21 (1.02 to 4.81)

2.23 (0.98 to 5.05)

0.054

rs2228570,VDR

GG

137

76 (55 %)

Ref

0.96

GA

83

47 (57 %)

1.04 (0.60 to 1.81)

-

-

AA

15

8 (53 %)

0.92 (0.31 to 2.67)

-

-

rs2060793, CYP2R1

GG

112

62 (55 %)

Ref

0.81

AG

106

62 (58 %)

0.80 (0.22 to 2.94)

-

-

AA

10

5 (50 %)

1.13 (0.66 to 1.94)

-

-

rs10500804, CYP2R1

GG

59

34 (58 %)

Ref

0.34

GT

120

69 (58 %)

0.99 (0.53 to 1.87)

-

-

TT

52

24 (46 %)

0.63 (0.29 to 1.33)

-

-

rs10766197, CYP2R1

AA

52

29 (56 %)

Ref

0.60

AG

124

72 (58 %)

1.18 (0.57 to 2.11)

-

-

GG

56

28 (50 %)

0.84 (0.37 to 1.72)

-

-

rs7041, DBP

AA

55

34 (62 %)

Ref

0.57

AC

106

57 (54 %)

0.72 (0.37 to 1.47)

-

-

CC

71

38 (54 %)

0.71 (0.34 to 1.45)

-

-

rs4588,DBP

GG

122

66 (54 %)

Ref

0.14

GT

91

49 (54 %)

0.99 (0.57 to 1.70)

-

-

TT

21

16 (76 %)

2.71 (0.93 to 7.88)

-

-