Factor | Survival group (n = 30) | Fatality group (n = 15) | p-value (univariate) | p-value (multivariate) |
---|---|---|---|---|
Gender | Â | Â | 0.044 | Â |
 Male | 17 (56.7) | 13 (86.7) |  |  |
 Female | 13 (43.3) | 2 (13.3) |  | 0.104 |
Age (years) | 13 (4-19) | 11 (1-19) | 0.111 | Â |
Underlying disease | Â | Â | 0.296 | Â |
 Acute myeloid leukemia | 12 (40.0) | 7 (46.7) |  |  |
 Acute lymphoblastic leukemia | 13 (43.3) | 4 (26.7) |  |  |
 Severe aplastic anemia | 5 (16.7) | 2 (13.3) |  |  |
 Undifferentiated acute leukemia | 0 (0.0) | 1 (6.7) |  |  |
 Non-Hodgkin lymphoma | 0 (0.0) | 1 (6.7) |  |  |
Remission status of the underlying diseasea | Â | Â | 0.016 | Â |
 Complete remission status | 9 (36.0) | 0 (0.0) |  |  |
 Not complete remission status | 16 (64.0) | 13 (100.0) |  | 1.000 |
Type of preceding chemotherapy | Â | Â | 0.035 | Â |
 No chemotherapy | 6 (20.0) | 1 (6.7) |  |  |
 Induction | 4 (13.3) | 0 (0.0) |  | 1.000 |
 Re-induction or salvage | 9 (30.0) | 9 (60.0) |  | 0.999 |
 Consolidation | 4 (13.3) | 0 (0.0) |  | 1.000 |
 Maintenance | 1 (3.3) | 0 (0.0) |  | 1.000 |
 Palliative | 1 (3.3) | 4 (26.7) |  | 0.999 |
 Allogeneic hematopoietic cell transplantation | 5 (16.7) | 1 (6.7) |  | 1.000 |
Previous history of hematopoietic cell transplantation | 14 (46.7) | 8 (53.3) | 0.673 | Â |
Previous history of invasive aspergillosis | 4 (13.3) | 1 (6.7) | 0.651 | Â |
Duration of fever (days) | 2 (0–10) | 3 (0–17) | 0.419 |  |
Duration of neutropenia at the beginning of antifungal therapy | Â | Â | 1.000 | Â |
 ≤2 weeks | 14 (46.7) | 7 (46.7) |  |  |
 >2 weeks | 16 (53.3) | 8 (53.3) |  |  |
Presence of other accompanying infections | 11 (36.7) | 4 (26.7) | 0.502 | Â |
Chest computed tomography findings | Â | Â | Â | Â |
 Consolidations with a halo sign | 21 (70.0) | 14 (93.3) | 0.129 |  |
 Consolidations without a halo sign | 9 (30.0) | 1 (6.7) | 0.129 |  |
 Air-crescent sign | 0 (0.0) | 0 (0.0) | NA |  |
 Cavity | 1 (3.3) | 1 (6.7) | 1.000 |  |
Positive serum galactomannan results | 23 (76.7) | 14 (93.3) | 0.234 | Â |