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Table 2 Multilocus sequence typing [46] of Malawian CPS locus variants

From: High multiple carriage and emergence of Streptococcus pneumoniae vaccine serotype variants in Malawian children

    

MLST house keeping genes

 

Strain ID

Serotype

Country sampled

Sequence Type (ST)

aroE

gdh

gki

recP

spi

xpt

ddl

Closest Matching ST*

JF911504.1

6B-III

Netherlands

Novel

7

6

1

8

6

1

14

 

JF911507.1

6B-III

Netherlands

90

5

6

1

2

6

3

4

 

ERS096173

6B

Malawi

Novel

2

8

1

10

17

1

19

2863 (33D) (DLV)

4441 (6C) (DLV)

5266 (22A) (DLV)

ERS096172

6B

Malawi

Novel

1

43

29

1

77

1

14

8783 (NT) (DLV)

ERS096166

6B

Malawi

Novel

10

9

4

5

15

20

28

6382 (6A) (SLV)

7744 (6A) (SLV)

ERS096165

6B

Malawi

Novel

10

9

4

5

15

4

2

6382 (6A) (DLV)

7744 (6A) (DLV)

ERS096169

6B

Malawi

Novel

54

5

4

5

36

142

269

8050 (6A) (SLV)

ERS096157

19A

Malawi

2062

1

5

53

32

14

20

199

 

ERS096159

20

Malawi

Novel

13

5

4

5

6

28

168

5392 (20) (DLV)

7651 (20) (DLV)

ERS096158

20

Malawi

5435

2

5

36

12

6

20

269

 
  1. JF911504.1 and JF911507.1 are 6B-III subtypes previously described in Europe [27]. Serotypes with sample accession numbers ERS096165 –ERS096173 represent carriage CPS locus variants of serotype 6B in Malawian children. All the Malawian 6B variants belonged to 6B-III subtypes based on phylogeny (data not shown). Also shown are Multilocus sequence typing [46] profiles of serotypes 19A and 20 CPS locus variants. *Reference information obtained from MLST database (speumoniae.mlst.net). SLV and DLV represent single locus variant or double locus variant respectively. ST represents sequence type