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Table 2 Antimicrobial prescriptions over past 12 months; cases and controls

From: An outbreak of multi-drug resistant Escherichia coli urinary tract infection in an elderly population: a case-control study of risk factors

 

Cases (N = 76)

Controls (N = 156)

p

n (%)

n (%)

Prescribed in any setting

   

Any antimicrobial prescriptions

68 (89)

111 (71)

<0.001

Any ‘resistant’

57 (75)

80 (51)

0.019

GP prescriptions

   

Any antimicrobial prescriptions

44 (58)

85 (54)

0.624

Any ‘resistant’

30 (39)

62 (40)

0.919

Cephalosporins

5 (7)

7 (5)

 

Macrolides

6 (8)

11 (7)

 

Nitrofurantoin

10 (13)

9 (6)

 

Penicillins

17 (22)

51 (33)

 

Amoxicillin

9 (12)

20 (13)

 

Quinolones

16 (21)

27 (17)

 

Tetracyclines

4 (5)

11 (7)

 

Trimethoprimb

18 (24)

29 (19)

 

Hospital prescriptionsc

N = 54

N = 84

 

Any antimicrobial prescriptions

45 (83)

52 (62)

0.007

Any ‘resistant’

38 (70)

28 (33)

<0.001

Gentamicin

11 (20)

7 (8)

 

Cephalosporins

13 (24)

26 (31)

 

Macrolides

6 (11)

14 (17)

 

Nitrofurantoin

7 (13)

3 (4)

 

Penicillins

25 (46)

18 (21)

 

Amoxicillin

7 (13)

5 (6)

 

Quinolones

26 (48)

18 (21)

 

Tetracyclines

3 (6)

1 (1)

 

Trimethoprimb

12 (22)

8 (10)

 
  1. a ‘Resistant’ = antimicrobials to which the MDR E coli was resistant, i.e. gentamicin, quinolones, trimethoprim, trimethoprim-sulfamethoxazole, and amoxicillin
  2. b Trimethoprim or trimethoprim-sulfamethoxazole
  3. c Among participants who had been hospitalized