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Table 2 Antimicrobial prescriptions over past 12 months; cases and controls

From: An outbreak of multi-drug resistant Escherichia coli urinary tract infection in an elderly population: a case-control study of risk factors

  Cases (N = 76) Controls (N = 156) p
n (%) n (%)
Prescribed in any setting    
Any antimicrobial prescriptions 68 (89) 111 (71) <0.001
Any ‘resistant’ 57 (75) 80 (51) 0.019
GP prescriptions    
Any antimicrobial prescriptions 44 (58) 85 (54) 0.624
Any ‘resistant’ 30 (39) 62 (40) 0.919
Cephalosporins 5 (7) 7 (5)  
Macrolides 6 (8) 11 (7)  
Nitrofurantoin 10 (13) 9 (6)  
Penicillins 17 (22) 51 (33)  
Amoxicillin 9 (12) 20 (13)  
Quinolones 16 (21) 27 (17)  
Tetracyclines 4 (5) 11 (7)  
Trimethoprimb 18 (24) 29 (19)  
Hospital prescriptionsc N = 54 N = 84  
Any antimicrobial prescriptions 45 (83) 52 (62) 0.007
Any ‘resistant’ 38 (70) 28 (33) <0.001
Gentamicin 11 (20) 7 (8)  
Cephalosporins 13 (24) 26 (31)  
Macrolides 6 (11) 14 (17)  
Nitrofurantoin 7 (13) 3 (4)  
Penicillins 25 (46) 18 (21)  
Amoxicillin 7 (13) 5 (6)  
Quinolones 26 (48) 18 (21)  
Tetracyclines 3 (6) 1 (1)  
Trimethoprimb 12 (22) 8 (10)  
  1. a ‘Resistant’ = antimicrobials to which the MDR E coli was resistant, i.e. gentamicin, quinolones, trimethoprim, trimethoprim-sulfamethoxazole, and amoxicillin
  2. b Trimethoprim or trimethoprim-sulfamethoxazole
  3. c Among participants who had been hospitalized