Table 2 Clinical and microbiologic characteristics associated with isolates of the biofilm producing and non-biofilm producing groups

Number of Isolates

113

74

Male

101 (89 %)

56 (76 %)

0.01

NS

Military

86 (76 %)

41 (55 %)

<0.01

NS

Combat Trauma

74 (65 %)

35 (47 %)

0.01

NS

Burn

54 (48 %)

27 (36 %)

0.13

NS

Median % TBSA burn (IQR)

60 % (37, 79)

55 % (48, 63)

0.36

Coronary Artery Disease

4 (4 %)

7 (9 %)

0.09

NS

Chronic Kidney Disease

1 (1 %)

1 (1 %)

0.76

ESRD

0 (0 %)

2 (3 %)

0.08

NS

Diabetes

6 (5 %)

11 (15 %)

0.03

NS

Median Hct on Culture Date g/dl (IQR)

24.2 (22, 30)

24.1 (22, 31)

0.67

Median WBC on Culture Date 10³ cells/μl (IQR)

9.6 (6, 13)

9 (6, 12)

0.62

Median ESR on Culture Date mm/hr (IQR)

95 (57, 114)

79 (67, 106)

0.77

Median CRP on Culture Date mg/dl (IQR)

16.6 (8, 24)

12.25 (5, 20)

0.21

Received Appropriate Empiric Antibiotics

47 (42 %)

32 (43 %)

0.74

Median Prior Duration of Antibiotics, Days (IQR)

4 (2, 8)

4 (2, 8)

0.52

A. calcoaceticus-baumannii complex (n = 53)

29 (55 %)

24 (45 %)

0.32

E. coli (n = 34)

5 (14 %)

29 (85 %)

<0.001

0.01

K. pneumoniae (n = 44)

32 (71 %)

12 (27 %)

0.06

NS

P. aeruginosa (n = 34)

28 (82 %)

6 (18 %)

<0.01

<0.01

S. aureus (n = 22)

19 (86 %)

3 (14 %)

0.01

NS

MSSA (n = 6)

5 (83 %)

1 (17 %)

0.24

MRSA (n =16)

14 (87.5 %)

2 (12.5 %)

0.02

0.02

Polymicrobial Event^a

39 (35 %)

20 (27 %)

0.28

Blood Culture

20 (18 %)

21 (28 %)

0.08

NS

Central Line Associated

2 (10 %, n = 20)

4 (19 %, n = 21)

0.09

NS

Respiratory Culture

10 (9 %)

1 (1 %)

0.03

NS

Urine Culture

3 (3 %)

18 (24 %)

<0.01

NS

Foley Catheter Associated

1 (33 %, n = 3)

4 (22 %, n = 18)

0.50

Wound Culture

80 (71 %)

34 (46 %)

<0.01

NS

Orthopedic Device Related

15 (19 %, n = 80)

4 (12 %, n = 34)

<0.01

NS

Median Number of Surgeries (IQR)

5.5 (2, 9)

6 (2, 10)

0.56