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Table 2 Comparison of diagnostic methods for the detection of Mtb in hospitalized versus ambulatory and in smear-positive versus smear-negative patients

From: Evaluation of Microscopic Observation Drug Susceptibility (MODS) and the string test for rapid diagnosis of pulmonary tuberculosis in HIV/AIDS patients in Bolivia

A.

All patients

Hospitalized patients

Ambulatory patients

TB+ (n = 48)

Diagnostic yield (95 % CI)

TB+ (n = 35)

Diagnostic yield (95 % CI)

TB+ (n = 13)

Diagnostic yield (95 % CI)

MODS

46

95.8 % (85.7-99.5)

34

97.1 % (85.1-99.9)

12

92.3 % (64.0-99.8)

LJ

38

79.2 % (65.0-89.5)

31

88.6 % (73.3-96.8)

7

53.8 % (25.1-80.8)

ZN

30

62.5 % (47.3-76.0)

22

62.9 % (44.9-78.5)

8

61.5 % (31.6-86.1)

B.

All patients

Smear-positive

Smear-negative

TB+ (n = 48)

Diagnostic yield (95 % CI)

TB+ (n = 30)

Diagnostic yield (95 % CI)

TB+ (n = 18)

Diagnostic yield (95 % CI)

MODS

46

95.8 % (85.7-99.5)

29

96.6 % (82.8-99.9)

17

94.4 % (72.7-99.9)

LJ

38

79.2 % (65.0-89.5)

27

90.0 % (73.4-97.9)

11

61.0 % (35.7-82.7)

  1. TB+ was defined as any patient with sputum or gastric sample that yielded a positive culture result by LJ or MODS. As the reference standard is a composite from all tests that are being evaluated, we can only comment on diagnostic yield rather than sensitivity and specificity. Panel A: Comparison of diagnostic yield of MODS versus LJ and ZN in all patients, hospitalized patients, and ambulatory patients who were TB positive. Panel B: Subgroup comparison of the diagnostic yield of MODS versus LJ in culture positive patients, sub-grouped into all patients, smear positive patients, and smear negative patients
  2. n number of patients in each group; CI confidence interval; TB + samples tested positive for Mtb by each respective method (MODS, LJ, or ZN)
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BMC Infectious Diseases

ISSN: 1471-2334

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