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Table 2 Unadjusted and adjusted baseline associates of psychological distress (K-10 score) at recruitment

From: Psychological distress and its relationship with non-adherence to TB treatment: a multicentre study

 

Univariate analysis

Multivariate analysis

 

Crude estimate (95 % CI)

P-value

Adjusted estimate (95 % CI)

P-value

Demographic and clinical characteristics

Age

0.045 (0.010. 0.083)

0.0132

0.031 (−0.003, 0.064)

0.0702

Male

−2.499 (−3.371, −1.627)

<0.0001

−1.447 (−2.278, −0.617)

0.0007

Previously had TB

−0.541 (−1.561, 0.479)

0.2987

0.980 (0.094, 1.866)

0.0304

HIV-infected

3.059 (2.172, 3.946)

<0.0001

0.061 (−0.763, 0.885)

0.8844

TBscore

0.698 (0.481, 0.914)

<0.0001

1.000 (0.802, 1.199)

<0.0001

Allocation arm Xpert MTB/RIF

−0.245 (−1.118, 0.628)

0.5824

-

-

Culture-confirmed TB

−0.450 (−1.468, 0.568)

0.3866

-

-

Substance use

Tobacco smoker

−3.123 (−4.078, −2.169)

<0.0001

-

-

Alcohol consumption

    

 Never

1.00 (reference)

N/A

1.00 (reference)

N/A

 Social

−3.124 (−4.203, −2.045)

<0.0001

−0.599 (−1.592, 0.395)

0.2378

 Regular

−2.061 (−3.212, −0.910)

0.0005

−0.001 (−1.041, 1.039)

0.9991

 Heavy

−1.362 (−3.496, 0.773)

0.2115

3.082 (1.256,4.907)

0.0010

Educational characteristics

Educational level

    

 None

−6.496 (−10.722, −2.251)

0.0027

−1.667 (−5.155, 1.82)

0.3489

 Primary school

−3.751 (−7.664, 0.160)

0.0604

0.420 (−2.771, 3.610)

0.7966

 Middle school

−5.224 (−9.140, −1.308)

0.0090

−0.528 (−3.762, 2.707)

0.7492

 High School

−4.792 (−8.700, −0.884)

0.0164

−0.324 (−3.508, 2.860)

0.8418

 Intermediate or post-high school diploma

−3.5906 (−7.674, 0.493)

0.0850

0.988 (−2.378, 4.354)

0.5651

 Graduate or post-graduate

0.00 (reference)

N/A

0.00 (reference)

N/A

TB health literacy score

−0.409 (−0.551, −0.267)

<0.0001

-

-

Economic characteristics

Unemployed or retired

2.877 (2.012, 3.742)

<0.0001

-

-

Personal monthly income

    

 Tier 1

1.578 (−1.982, 5.139)

0.3850

-

-

 Tier 2

−1.291 (−4.879, 2.296)

0.4806

-

-

 Tier 3

−0.804 (−4.637, 3.028)

0.6809

-

-

 Tier 4

0.00 (reference)

N/A

-

-

Household monthly income

    

 Tier 1

−1.802 (−4.187, 0.583)

0.1389

-

-

 Tier 2

−2.352 (−4.718, 0.015)

0.0516

-

-

 Tier 3

−2.066 (−4.676, 0.543)

0.1209

-

-

 Tier 4

0.00 (reference)

N/A

-

-

Sites

 Cape Town

0.565 (−0.637, 1.767)

0.3569

1.525 (0.142, 2.907)

0.0309

 Harare

10.648 (9.440, 11.856)

<0.0001

11.070 (9.802, 12.340)

<0.0001

 Lusaka

−0.636 (−1.845, 0.574)

0.3031

−1.281 (−2.623, 0.061)

0.0616

 Mbeya

8.423 (6.603, 10.243)

<0.0001

6.923 (4.9945, 8.911)

<0.0001

 Durban

0.00 (reference)

N/A

0.00 (reference)

N/A

  1. Cells marked with a dash indicate variables excluded from the final multivariate model