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Table 3 Distribution of AIDS cases according to AIDS-defining diseases and odds ratiosa for early mortality. Italy, 1999-2009

From: Risk factors for early mortality after AIDS in the cART era: A population-based cohort study in Italy

  AIDS cases Early mortality  
  No. No. (%) OR (95 % CI)
AIDS-defining diseasesb
Infectious diseases
Pneumocystis carinii pneumonia 2650 393 (14.8) 1c
 Tuberculosis 1089 126 (11.6) 0.81 (0.65-1.00)
 Candidiasis 2943 404 (13.7) 0.84 (0.72-0.98)
 Recurrent pneumonia 466 62 (13.3) 0.91 (0.68-1.23)
 Other infections 1476 266 (18.0) 1.22 (1.02-1.45)
 Brain toxoplasmosis 856 175 (20.4) 1.43 (1.16-1.75)
Neoplasms
 Invasive cervical cancer 104 9 (8.7) 0.59 (0.29-1.24)
 Kaposi sarcoma 773 80 (10.4) 0.82 (0.63-1.07)
 Immunoblastic lymphoma 707 234 (33.1) 3.18 (2.59-3.89)
 Burkitt lymphoma 286 95 (33.2) 3.48 (2.62-4.62)
 Primary brain lymphoma 85 54 (63.5) 11.66 (7.32-18.57)
Other conditions
 HIV encephalopathy 999 231 (23.1) 1.55 (1.28-1.88)
 HIV wasting syndrome 1655 436 (26.3) 1.78 (1.52-2.09)
 Progressive multifocal leukoencephalopathy 463 192 (41.5) 4.21 (3.37-5.27)
No. of AIDS-defining diseases at diagnosis
 1 11670 2048 (17.6) 1c
 2 2261 510 (22.6) 1.27 (1.13-1.42)
 ≥3 621 199 (32.1) 1.97 (1.64-2.37)
  1. aOdds ratios (OR) and 95 % confidence intervals (CI) estimated using multivariate logistic regression models adjusted for age, gender, area of residence, education, HIV transmission mode, year and CD4 cell count at AIDS diagnosis
  2. bFor patients with more than one AIDS-defining disease, only the most severe was considered
  3. cReference category