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Table 1 Distribution of AIDS cases by selected characteristics collected at AIDS diagnosis and odds ratiosa for early mortality. Italy, 1999-2009

From: Risk factors for early mortality after AIDS in the cART era: A population-based cohort study in Italy

  AIDS cases (No. = 14552) Early mortality (No. = 2757)  
  No. No. (%) OR (95 % CI)
Age at AIDS diagnosis (yrs)
 13-34 2839 362 (12.8) 1b
 35-39 3543 545 (15.4) 1.19 (1.03-1.37)
 40-44 3305 597 (18.1) 1.48 (1.28-1.71)
 45-49 1944 410 (21.1) 1.98 (1.69-2.32)
 50-54 1104 253 (22.9) 2.38 (1.98-2.87)
 55-59 764 181 (23.7) 2.59 (2.10-3.19)
 ≥60 1053 409 (38.8) 5.28 (4.41-6.32)
χ2 for trend (p-value)    373.13 (p < 0.01)
Gender
 Male 11388 2203 (19.3) 1b
 Female 3164 554 (17.5) 1.04 (0.93-1.16)
Area of residencec
 Centre 3481 594 (17.1) 1b
 North 8043 1534 (19.1) 1.14 (1.02-1.27)
 South 2836 594 (20.9) 1.35 (1.19-1.54)
Education (yrs)
 ≥9 3563 563 (15.8) 1d
 6-8 6603 1202 (18.2) 1.11 (0.99-1.24)
 ≤5 2127 519 (24.4) 1.25 (1.08-1.44)
 Unknown 2259 473 (20.9) 1.23 (1.07-1.42)
χ2 for trend (p-value)d    9.57 (p < 0.01)
HIV transmission modee
 Heterosexual intercourse 5088 887 (17.4) 1b
 Homosexual male intercourse 2862 472 (16.5) 1.04 (0.91-1.19)
 Injecting drug use 5646 1147 (20.3) 1.71 (1.53-1.91)
Year at AIDS diagnosis
 1999-2002 6519 1255 (19.3) 1b
 2003-2006 5084 965 (19.0) 0.92 (0.84-1.02)
 2007-2009 2949 537 (18.2) 0.84 (0.74-0.94)
χ2 for trend (p-value)    8.79 (p < 0.01)
CD4 cell count/mm3 at AIDS diagnosisc
 ≥350 1135 140 (12.3) 1b
 200-349 1623 286 (17.6) 1.45 (1.17-1.81)
 50-199 5369 984 (18.3) 1.57 (1.29-1.90)
 <50 5957 1187 (19.9) 1.87 (1.55-2.27)
χ2 for trend (p-value)    46.80 (p < 0.01)
Use of pre-AIDS antiretroviral drugsc
 No 8834 1620 (18.3) 1b
 Yes 5265 1005 (19.1) 1.12 (1.02-1.23)
  1. aOdds ratios (OR) and 95 % confidence intervals (CI) estimated using multivariate logistic regression models adjusted for age, gender, area of residence, education, HIV transmission mode, year and CD4 cell count at AIDS diagnosis
  2. bReference category
  3. cThe sum does not add up to the total because of missing values
  4. dUnknown excluded
  5. eThe sum does not add up to the total because of other, not considered, HIV transmission modes and missing values