Table 3 Association of the characteristics of the index leprosy cases with seropositivity among the household contacts
Variable | Total of participants | Anti PGL-I seropositivity | PR | 95 % CI | P value |
|---|---|---|---|---|---|
n | n (%) | ||||
Operational classification | |||||
Paucibacillary | 172 | 14 (8.1) | 1 | ||
Multibacillary | 204 | 36 (17.6) | 2.17 | 1.22–3.86 | 0.009 |
Number of lesions | |||||
≤5 | 244 | 29 (11.9) | 1 | ||
>5 | 145 | 24 (16.6) | 1.39 | 0.84–2.31 | 0.199 |
Clinical form | |||||
Indeterminate | 113 | 13 (11.5) | 1 | ||
Tuberculoid | 73 | 3 (4.1) | 0.36 | 0.11–1.16 | 0.087 |
Borderline | 119 | 19 (16.0) | 1.39 | 0.72–2.69 | 0.332 |
Virchownian | 72 | 14 (19.4) | 1.69 | 0.83–3.43 | 0.147 |
Slit skin smear status | |||||
Negative | 199 | 26 (13.1) | 1 | ||
Positive | 103 | 13 (12.6) | 0.97 | 0.52–1.81 | 0.914 |
Bacterial index | |||||
<2 | 21 | 3 (14.3) | 1 | ||
≥2 | 361 | 47 (13.0) | 0.91 | 0.31–2.71 | 0.868 |
Degree of disability at diagnosis | |||||
Degree 0 | 215 | 19 (8.8) | 1 | ||
Degree 1 | 136 | 22 (16.2) | 1.83 | 1.02–3.26 | 0.041 |
Degree 2 | 28 | 6 (21.4) | 2.42 | 1.02–5.74 | 0.045 |
Number of damaged nerves | |||||
≤1 | 70 | 5 (7.1) | 1 | ||
>1 | 69 | 11 (15.9) | 2.23 | 0.82–6.08 | 0.119 |
Year of diagnosis | |||||
2006 | 82 | 9 (11.0) | 1 | ||
2007 | 76 | 14 (18.4) | 1.68 | 0.77–3.68 | 0.197 |
2008 | 79 | 10 (12.7) | 1.15 | 0.50–2.68 | 0.741 |
2009 | 82 | 9 (11.0) | 1 | 0.42–2.38 | 1.000 |
2010 | 47 | 5 (10.6) | 0.97 | 0.35–2.70 | 0.952 |
2011 | 339 | 5 (25.0) | 2.28 | 0.82–6.35 | 0.116 |